Cpa1

  • Official Full Name

    carboxypeptidase A1 (pancreatic)
  • Overview

    Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a monomeric pancreatic exopeptidase involved in zymogen inhibition.
  • Synonyms

    CPA1;carboxypeptidase A1 (pancreatic);CPA;carboxypeptidase A1;Carboxypeptidase A1 precursor;CBPA1_HUMAN;Pancreatic carboxypeptidase A1;Procarboxypeptidase A1 pancreatic;OTTHUMP00000212514;OTTHUMP00000212515;OTTHUMP00000212518

Recombinant Proteins

  • Mouse
  • Human
  • Rat
  • Zebrafish
  • Chicken
  • HEK293
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • Human Cell
  • Mammalian cells
  • In Vitro Cell Free System
  • HEK293T
  • His
  • His&T7
  • GST
  • Non
  • His&Fc&Avi
  • His&Myc
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
Cpa1-2287M Active Recombinant Mouse Cpa1 protein, His-tagged HEK293 Mouse His 1-419 a.a.
CPA1-3176H Active Recombinant Human CPA1 protein, His-tagged HEK293 Human His Met1-Tyr419
Cpa1-1432R Recombinant Rat Cpa1 protein, His & T7-tagged E.coli Rat His&T7 Thr205~Tyr419
CPA1-1561R Recombinant Rat CPA1 Protein Mammalian Cell Rat His
CPA1-1768H Recombinant Human CPA1 Protein, GST-tagged Wheat Germ Human GST
CPA1-2686Z Recombinant Zebrafish CPA1 Mammalian Cell Zebrafish His
CPA1-6153C Recombinant Chicken CPA1 Mammalian Cell Chicken His
CPA1-2171HCL Recombinant Human CPA1 cell lysate Human Cell Human Non
CPA1-2478MCL Recombinant Mouse CPA1 cell lysate Human Cell Mouse Non
CPA1-1055H Recombinant Human CPA1 Protein (Lys17-Tyr419), C-His tagged Mammalian cells Human His Lys17-Tyr419
CPA1-1218R Recombinant Rat CPA1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
CPA1-1218R-B Recombinant Rat CPA1 Protein Pre-coupled Magnetic Beads HEK293 Rat
CPA1-2047HF Recombinant Full Length Human CPA1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 419 amino acids
Cpa1-2719R Recombinant Rat Cpa1 protein, His&Myc-tagged E.coli Rat His&Myc 111-419aa
CPA1-3303H Recombinant Human CPA1 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
Cpa1-431M Recombinant Mouse Cpa1 Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    Cpa1 involved in several pathways and played different roles in them. We selected most pathways Cpa1 participated on our site, such as Pancreatic secretion,Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cpa1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein digestion and absorption KCNK5,LOC780933,COL4A1,ELN,MEP1A,CELA3A,SLC7A8,COL18A1,COL6A5,SLC36A1
    Pancreatic secretion AMY2A4,RAP1A,RAB27B,CLCA1,PLA2G2A,RHOA,ATP1B2,PLA2G2D,ITPR1,CELA2B

    Protein Function

    Cpa1 has several biochemical functions, for example, metallocarboxypeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Cpa1 itself. We selected most functions Cpa1 had, and list some proteins which have the same functions with Cpa1. You can find most of the proteins on our site.

    Function Related Protein
    metallocarboxypeptidase activity AGBL1,CPA2,CPE,CPDB,CPB2,CPN1,CPA6,AGBL4,CPD,PEPD
    zinc ion binding NEIL1,RNF222,FBXO30B,PHF21B,ADAM20,RNF19B,RNF128A,RP9,TRIM45,MSL2B

    Interacting Protein

    Cpa1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cpa1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cpa1.

    ARRB1

    Resources

    References

    • Overton, ET; Goepfert, PA; et al. Intranasal seasonal influenza vaccine and a TLR-3 agonist, rintatolimod, induced cross-reactive IgA antibody formation against avian H5N1 and H7N9 influenza HA in humans. VACCINE 32:5490-5495(2014).
    • Smith, GE; Flyer, DC; et al. Development of influenza H7N9 virus like particle (VLP) vaccine: Homologous A/Anhui/1/2013 (H7N9) protection and heterologous A/chicken/Jalisco/CPA1/2012 (H7N3) cross-protection in vaccinated mice challenged with H7N9 virus. VACCINE 31:4305-4313(2013).

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