COL13A1
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Official Full Name
collagen, type XIII, alpha 1 -
Overview
This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined. -
Synonyms
COL13A1;collagen, type XIII, alpha 1;collagen alpha-1(XIII) chain;CODA1_HUMAN;collagentype XIII alpha 1;collagen alpha 1(XIII) chain;COLXIIIA1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Col13a1-325M |
Active Recombinant Mouse Col13a1, His-tagged
|
Mammalian cells | Mouse | His | 107-565 a.a. |
|
| Col13a1-465M |
Active Recombinant Mouse Collagen, Type XIII, Alpha 1, His-tagged
|
Mammalian cells | Mouse | His | 107-565 a.a. |
|
| COL13A1-3717M | Recombinant Mouse COL13A1 Protein | Mammalian Cell | Mouse | His |
|
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| COL13A1-7379HCL | Recombinant Human COL13A1 293 Cell Lysate | HEK293 | Human | Non |
|
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| Col13a1-1846M | Recombinant Mouse Col13a1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
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| Col13a1-1846M-B | Recombinant Mouse Col13a1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
COL13A1 involved in several pathways and played different roles in them. We selected most pathways COL13A1 participated on our site, such as Collagen biosynthesis and modifying enzymes,Collagen degradation,Collagen formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL13A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Collagen biosynthesis and modifying enzymes | TLL2,COL28A1,COL6A1,SERPINH1B,ADAMTS2,PRP,SERPINH1,COL4A5,COL4A6,COL17A1 |
| Integrin cell surface interactions | JAM2B,COL23A1,ICAM4,COL16A1,F11R.2,COL9A1A,FBN1,BSG,COL9A1B,LOC100514666 |
| Extracellular matrix organization | ADAM8,PCOLCEA,BSG,ASPN,ITGB3A,MUSK,COL4A3,MATN4,FURINA,MGC174155 |
| Protein digestion and absorption | KCNE3,CTRL,MME,ATP1A1,COL6A5,KCNJ13,SLC3A1,COL10A1,PGA4,XPNPEP2 |
| Collagen degradation | MMP13,COL17A1,EMID2,COL15A1B,CTSLL,MMP11,COL19A1,ADAM10,CTSL1,ADAM9 |
| Collagen formation | SERPINH1A,TLDC2,COL17A1,COL23A1,PCOLCE2B,BMP1,TLL1,PCOLCE,LOXL4,LEPREL2 |
| Degradation of the extracellular matrix | MMP19,ADAMTS4,CMA1,BMP1,CTS7,CTSL1,MMP8,COL25A1,CTSK,BMP1A |
Protein Function
COL13A1 has several biochemical functions, for example, heparin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL13A1 itself. We selected most functions COL13A1 had, and list some proteins which have the same functions with COL13A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NMU,FRMPD4,R3HDM2,BID,CCDC116,OAZ1,GPRASP1,MEN1,SPTAN1,RMND5A |
| heparin binding | SLIT3,RSPO2,SELL,Epy,FGF14,FGFBP1,THBS1,COMP,PTN,CCL7 |
Interacting Protein
COL13A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL13A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL13A1.
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