CNN2
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Official Full Name
calponin 2 -
Overview
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
CNN2;calponin 2;calponin-2;smooth muscle;Calponin H2;Calponin H2, smooth muscle;CNN2_HUMAN;Neutral calponin
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- Mammalian cells
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
- His&SUMO
- Flag
Involved Pathway
CNN2 involved in several pathways and played different roles in them. We selected most pathways CNN2 participated on our site, such as Myometrial Relaxation and Contraction Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CNN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Myometrial Relaxation and Contraction Pathways | RGS6,MYLK2,CNN1,RGS20,PKIG,IGFBP2,CRH,RGS18,RGS11,RAMP3 |
Protein Function
CNN2 has several biochemical functions, for example, actin binding,calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CNN2 itself. We selected most functions CNN2 had, and list some proteins which have the same functions with CNN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calmodulin binding | CALD1B,ATP2B1,SRY,CAMSAP1,EDF1,ORAI1,MYH4,SNTB1,MYH7,PDE1A |
| actin binding | VCL,LSP1,XIRP2,FHL3,PHACTR4,ABRAB,GIPC1,TAGLN,DMD,TNS1 |
Interacting Protein
CNN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CNN2.
pi3p;FN1
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References
- Qiu, JY; Liu, P; et al. Low-grade myofibroblastic sarcomas of the maxilla. ONCOLOGY LETTERS 9:619-625(2015).
- Xie, SL; Yang, HY; et al. Salivary duct carcinoma of the parotid gland: A case report and review of the literature. ONCOLOGY LETTERS 9:371-374(2015).
