CMAS
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Official Full Name
cytidine monophosphate N-acetylneuraminic acid synthetase -
Overview
The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus. -
Synonyms
CMAS;cytidine monophosphate N-acetylneuraminic acid synthetase;N-acylneuraminate cytidylyltransferase;CMP Neu5Ac synthetase;CMP-NeuNAc synthase;CMP-Neu5Ac synthetase;CMP-NeuNAc synthetase;CMP-N-acetylneuraminic acid synthase;CMP-N-acetylneuraminic
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- E.coli
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CMAS involved in several pathways and played different roles in them. We selected most pathways CMAS participated on our site, such as Amino sugar and nucleotide sugar metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CMAS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Amino sugar and nucleotide sugar metabolism | GMPPA,GMPPAB,UGP2,UAP1,AMDHD2,CMAH,PGM2,CHIA.4,GFPT2,CHIT1 |
| Metabolic pathways | MTHFD1L,PDHA2,PIP5K1AB,DPYS,EXT1A,ST3GAL4,NDUFV1,IMPDH1B,NFS1,CYP3A65 |
Protein Function
CMAS has several biochemical functions, for example, N-acylneuraminate cytidylyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CMAS itself. We selected most functions CMAS had, and list some proteins which have the same functions with CMAS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| N-acylneuraminate cytidylyltransferase activity | CMASB,CMASA,NANS |
Interacting Protein
CMAS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CMAS here. Most of them are supplied by our site. Hope this information will be useful for your research of CMAS.
LRRK2;ntpa_bacan;ssrna_cg;Srp72;Cep170;Smad6;C1qbp
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