CINP
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Official Full Name
cyclin-dependent kinase 2 interacting protein -
Overview
The protein encoded by this gene interacts with CDK2, MCM5, and CDC7, and is associated with the origin recognition complex protein ORC2. It acts as a homodimer and is involved in replication and ATR-mediated checkpoint signaling. Three transcript variants encoding different isoforms have been found for this gene. -
Synonyms
CINP;cyclin-dependent kinase 2 interacting protein;cyclin-dependent kinase 2-interacting protein;MGC849;CINP protein;CDK2-interacting protein;CINP_HUMAN;Cyclin dependent kinase 2 interacting protein
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Rhesus macaque
- Wheat Germ
- E.coli
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- T7
- His&Fc&Avi
- Myc&DDK
- His&SUMO
Involved Pathway
CINP involved in several pathways and played different roles in them. We selected most pathways CINP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CINP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CINP has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CINP itself. We selected most functions CINP had, and list some proteins which have the same functions with CINP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MRPL45,HUWE1,PSMC2,NR2C2AP,CUL4B,MRPL49,FIGNL1,PSME3,RECQL4,STOML1 |
Interacting Protein
CINP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CINP here. Most of them are supplied by our site. Hope this information will be useful for your research of CINP.
REL;GOLGA2;SYCE1;FBF1;ATRIP;BLZF1;C1orf109
Resources
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References
- Atsaves, V; Lekakis, L; et al. The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK plus anaplastic large cell lymphoma. BRITISH JOURNAL OF HAEMATOLOGY 167:514-523(2014).
- Sidhu, PS; Teske, K; et al. Anticancer activity of VDR-coregulator inhibitor PS121912. CANCER CHEMOTHERAPY AND PHARMACOLOGY 74:787-798(2014).
