CIB2
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Official Full Name
calcium and integrin binding family member 2 -
Overview
The amino acid sequence the protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. This suggests that the encoded protein may be a Ca2+-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunit (DNA-PKcs). -
Synonyms
CIB2;calcium and integrin binding family member 2;calcium and integrin-binding family member 2;KIP2;KIP 2;2810434I23Rik;kinase-interacting protein 2;DNA-dependent protein kinase catalytic subunit-interacting protein 2
Recombinant Proteins
- Zebrafish
- Human
- Rat
- Rhesus macaque
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CIB2-10971Z | Recombinant Zebrafish CIB2 | Mammalian Cell | Zebrafish | His |
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| CIB2-1357H | Recombinant Human CIB2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| CIB2-1413R | Recombinant Rat CIB2 Protein | Mammalian Cell | Rat | His |
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| CIB2-1800H | Recombinant Human CIB2 protein, His-tagged | E.coli | Human | His | Met1-Ile187 |
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| CIB2-27244TH | Recombinant Human CIB2, His-tagged | E.coli | Human | His | 187 amino acids |
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| CIB2-3474H | Recombinant Human CIB2, His-tagged | E.coli | Human | His |
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| CIB2-876R | Recombinant Rhesus monkey CIB2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| CIB2-7498HCL | Recombinant Human CIB2 293 Cell Lysate | HEK293 | Human | Non |
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| CIB2-1071R | Recombinant Rat CIB2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| CIB2-1071R-B | Recombinant Rat CIB2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| CIB2-1841HF | Recombinant Full Length Human CIB2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 187 amino acids |
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| CIB2-702R | Recombinant Rhesus Macaque CIB2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| CIB2-702R-B | Recombinant Rhesus Macaque CIB2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
CIB2 involved in several pathways and played different roles in them. We selected most pathways CIB2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CIB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CIB2 has several biochemical functions, for example, calcium ion binding,integrin binding,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CIB2 itself. We selected most functions CIB2 had, and list some proteins which have the same functions with CIB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| integrin binding | CTGFA,ITGB5,TGFBI,IGF1,THBS4,CTGFB,SYK,COL5A1,S1PR2,S1PR3 |
| protein homodimerization activity | SDCBP,DMRTC1C2,DAXX,Bcl2a1b,UGT1A1,PTPRE,CHKA,MVD,INHBB,DGCR8 |
| protein binding | FES,SETBP1,HAPLN2,IFT57,DIAPH1,B9D2,FAM131B,MEF2A,MAT2A,S100A16 |
| calcium ion binding | CABP1A,RHBDL3,CDH15,CAPNS1A,HSPA5,CDH8,THBS2,GRIN1,VCANB,EFCAB5 |
| magnesium ion binding | IDH2,DCTPP1,SIK3,NCS1,PPA1B,NUDT3,IMPA2,ADPRH,BPNT1,CDC42BPA |
Interacting Protein
CIB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CIB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CIB2.
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References
- Aparisi, MJ; Aller, E; et al. Targeted next generation sequencing for molecular diagnosis of Usher syndrome. ORPHANET JOURNAL OF RARE DISEASES 9:-(2014).
- Eisenberger, T; Di Donato, N; et al. Targeted and Genomewide NGS Data Disqualify Mutations in MYO1A, the "DFNA48 Gene", as a Cause of Deafness. HUMAN MUTATION 35:565-570(2014).
