CHUK

  • Official Full Name

    conserved helix-loop-helix ubiquitous kinase

  • Synonyms

    CHUK;conserved helix-loop-helix ubiquitous kinase;TCF16;inhibitor of nuclear factor kappa-B kinase subunit alpha;IkBKA;IKK alpha;IKK1;IKKA;NFKBIKA;TCF-16;IKK-a kinase;I-kappa-B kinase 1;I-kappa-B kinase-alpha;transcription factor 16;IkB kinase alpha subunit;Nuclear factor NFkappaB inhibitor kinase alpha;IKBKA;IKK-alpha

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Sf9 Cells
  • E.coli
  • Insect Cells
  • Sf21 Cells
  • Mammalian Cells
  • Wheat Germ
  • Non
  • His
  • GST
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
CHUK-27562TH Recombinant Human CHUK Sf9 Cells Human Non 745 amino acids
CHUK-3943H Recombinant Human CHUK protein, His-tagged E.coli Human His 516 - 620 aa
CHUK-5129H Active Recombinant Human CHUK Protein, GST-tagged Insect Cells Human GST
CHUK-3422HF Active Recombinant Full Length Human CHUK Protein, GST-tagged Sf21 Cells Human GST Full L. 1-745(end)
CHUK-7671HF Active Recombinant Full Length Human CHUK Protein, DDK-tagged, Biotinylated Sf21 Cells Human Flag Full L. 1-745(end)
CHUK-8633HF Active Recombinant Full Length Human CHUK Protein, DDK-tagged, Biotinylated Sf21 Cells Human Flag Full L. 1-745(end)
CHUK-1004H Recombinant Human Conserved Helix-Loop-Helix Ubiquitous Kinase, GST-tagged Sf9 Cells Human GST Full L.
CHUK-10645Z Recombinant Zebrafish CHUK Mammalian Cells Zebrafish His
CHUK-1351H Recombinant Human CHUK Protein, GST-tagged Wheat Germ Human GST
CHUK-2119C Recombinant Chicken CHUK Mammalian Cells Chicken His
CHUK-52H Recombinant Human CHUK protein, Flag-tagged, Biotinylated Insect Cells Human Flag 1-745 a.a.
CHUK-675H Recombinant Human CHUK, His-tagged Insect Cells Human His Full L.

    Involved Pathway

    CHUK involved in several pathways and played different roles in them. We selected most pathways CHUK participated on our site, such as AGE/RAGE pathway,AKT phosphorylates targets in the cytosol,Activated TLR4 signalling, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHUK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    AGE/RAGE pathway DDOST,JUN,AGER,MMP13,EGFR,LGALS3,ATF2,DIAPH1,JAK2,TIRAP
    Activation of NF-kappaB in B cells MALT1
    Acute myeloid leukemia AKT1,MAP2K2,IKBKG,MAPK1,MAPK3,HRAS,AKT2,RUNX1,PML,MTOR
    Activated TLR4 signalling ATF2,TAB1,DUSP6,SIGIRR,DUSP3B,NOD1,TICAM1,IRAK3,JUN,MAPK14
    AKT phosphorylates targets in the cytosol CDKN1A,CDKN1B,AKT3
    Adipocytokine signaling pathway POMCA,IKBKG,G6PC2,LEP,MAPK10,TRAF2,PPARA,NFKBIA,ACSL4A,PPARAB
    Adaptive Immune System MOV10,LILRB2,KIF4A,BLK,CD300C,RNF144B,SIGLEC5,LAIR2,SIGLEC10,NPEPPS

    Protein Function

    CHUK has several biochemical functions, for example, ATP binding,IkappaB kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHUK itself. We selected most functions CHUK had, and list some proteins which have the same functions with CHUK. You can find most of the proteins on our site.

    Function Related Protein
    protein kinase activity AKT3,PTK2BB,PRPF4BA,INSRA,MAP3K4,CDKL3,PRKACBB,MAP3K1,DYRK1AA,CAMKK1A
    protein heterodimerization activity BIRC5,ATF4,POLA2,BCL2L1,TCF12,BNIP3L,TCF3,ALG2,HMG20A,BOKB
    scaffold protein binding NLRP1,SCN5A,P2RY1,NLGN4X,TREM2,ADCY6,HOMER1,PANX1,PDE4D,NLGN4Y
    protein binding DDX5,GIPC2,TLE4,CDC23,SYCP1,ASAP3,TRIP6,GNA12,RRP7A,RANGAP1
    ATP binding CCT5,CTPS1A,ATM,MAPK8A,AK7A,SLK,KCNJ8,MAP3K12,NEK12,EPHB3
    IkappaB kinase activity IKBKB,IKBKE
    protein homodimerization activity SP100,ANO2,S100B,NR2C1,TBX18,PAH,CUBN,DPY30,ADH1,XCL1

    Interacting Protein

    CHUK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHUK here. Most of them are supplied by our site. Hope this information will be useful for your research of CHUK.

    IKBKG

    Resources

    Research Area

    Transcription Regulators in Endothelial Cells
    IkB Kinase (IKK)
    Natural Killer T (NKT) Cells
    IL-1 Family Signaling Molecules
    IL-17 Signaling Related Molecules

    References

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