CHP
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Official Full Name
chemotaxis-inhibiting protein CHIPS -
Overview
This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein -
Synonyms
chp;chemotaxis-inhibiting protein CHIPS;Chemotaxis inhibiting protein;secreted protein that specifically inhibits the activation of neutrophils and monocytes by binding to the formylated peptide receptor and the C5a receptor;blocks neutrophil migration towards the infection site and hinders the establishment of the initial
Recombinant Proteins
- Human
- Rat
- Staphylococcus aureus
- Staphylococcus Aureus
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- Yeast
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- His&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CHP-11197H | Recombinant Human CHP, GST-tagged | E.coli | Human | GST | 1-66a.a. | |
| CHP-1261H | Recombinant Human CHP Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CHP-1381R | Recombinant Rat CHP Protein | Mammalian Cell | Rat | His |
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| CHP-2583H | Recombinant Human Lcium Binding Protein P22, His-tagged | E.coli | Human | His |
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| CHP-7527HCL | Recombinant Human CHP 293 Cell Lysate | HEK293 | Human | Non |
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| CHP-1039R | Recombinant Rat CHP Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| CHP-1039R-B | Recombinant Rat CHP Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| chp-1111S | Recombinant Staphylococcus aureus chp protein, His&Myc-tagged | E.coli | Staphylococcus aureus | His&Myc | 29-149aa |
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| CHP-2168S | Recombinant Staphylococcus Aureus CHP Protein (29-149 aa), His-tagged | Yeast | Staphylococcus Aureus | His | 29-149 aa |
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| CHP-3214HF | Recombinant Full Length Human CHP Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 66 amino acids |
|
Involved Pathway
CHP involved in several pathways and played different roles in them. We selected most pathways CHP participated on our site, such as Alzheimers Disease,Calcium signaling in the CD4+ TCR pathway,Glycosaminoglycan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycosaminoglycan metabolism | HS3ST6,CSPG5B,STAB2,B3GNT2A,SLC26A2,MAPK1IP1L,OMD,VCANB,SLC35B2,CHST14 |
| Metabolism of carbohydrates | SLC26A1,OXSR1,LYVE1,UST,SLC25A12,HPSE,B3GAT2,EPM2A,B3GNT1,GLB1L |
| Metabolism | CYB5R3,NOSIP,PAOX,TCN1,NUDT10,NEU3,ACOT8,THEM5,SLC35B2,CLPS |
| Role of Calcineurin-dependent NFAT signaling in lymphocytes | FKBP8,RCAN1,RCAN2 |
| Hyaluronan uptake and degradation | STAB2,LYVE1 |
| Alzheimers disease | CASP9,CALM3,COX6A1,NDUFB6,NDUFB4,Atp5g2,NDUFB9,UQCR11,NDUFV1,NDUFB7 |
| Calcium signaling in the CD4+ TCR pathway | JUNB,BATF3,FKBP1A,CSF2,RCAN2,AKAP5,POU2F1,RCAN1 |
| Hyaluronan metabolism | STAB2,HAS3,KIAA1199,HAS1,LYVE1 |
Protein Function
CHP has several biochemical functions, for example, calcium ion binding,calcium-dependent protein binding,kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHP itself. We selected most functions CHP had, and list some proteins which have the same functions with CHP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | TPT1,FKBP14,PTBP3,SYT4,MYL5,DGKB,HPCA,CLSTN1,ANXA1A,PCDH2AB10 |
| potassium channel regulator activity | KCNAB2,SGK2A,LRRC26,ANK2,YWHAE,KCNAB1,KCNIP4,SGK3,KCNV1,KCNS3 |
| protein binding | MYOG,RAD21,RANBP2,SOX17,CDK7,S100A14,C4orf33,E2F5,LCK,GORASP1 |
| calcium-dependent protein binding | A2M,ANXA11,MMP13,S100A11,RAC3,TNNT3,MASP1,CALM3,VAMP2,SNAP25 |
| microtubule binding | SYBU,S100A8,KIF5A,RCC2,GAS2L2,APC,GAPDH,KIF15,APC2,PEX14 |
| transporter activity | CRABP2B,CPNE6,SYPL2B,SLCO1F2,ABCB8,SLC2A3A,CPNE7,AP1S2,AP1G1,ATP5G1 |
| protein kinase inhibitor activity | SOCS1B,NCK1,SOCS9,CAMK2N1A,NPM1,CD36,TAOK3,TESC,SOCS3A,TRIB3 |
| kinase binding | PARP16,PER3,GFAP,JAKMIP1,PRPSAP1,WWC2,PARK7,DLG3,CAB39,CHP1 |
Interacting Protein
CHP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHP here. Most of them are supplied by our site. Hope this information will be useful for your research of CHP.
Resources
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References
- Paniagua-Contreras, GL; Monroy-Perez, E; et al. Expression of enterotoxin-coding genes in methicillin-resistant Staphylococcus aureus strains isolated from Mexican haemodialysis patients. ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS 13:-(2014).
- Saito, T; Wada, H; et al. High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine. VACCINE 32:5901-5907(2014).
