CHD7
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Official Full Name
chromodomain helicase DNA binding protein 7 -
Overview
This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. [provided by RefSeq, Jul 2008] -
Synonyms
CHD7;chromodomain helicase DNA binding protein 7;CRG;HH5;IS3;KAL5;chromodomain-helicase-DNA-binding protein 7;CHARGE association;ATP-dependent helicase CHD7;chromodomain helicase DNA binding protein 7 isoform CRA_e
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Mammalian Cell
- HEK293F
- HEK293
- Non
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CHD7-1216H | Recombinant Human CHD7 Protein | E.coli | Human | Non |
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| CHD7-3382M | Recombinant Mouse CHD7 Protein | Mammalian Cell | Mouse | His |
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| CHD7-3513C | Recombinant Chicken CHD7 | Mammalian Cell | Chicken | His |
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| CHD7-4914H | Recombinant Human Chromodomain Helicase DNA Binding Protein 7, His-tagged | E.coli | Human | His | Full L. |
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| CHD7-08H | Recombinant Human CHD7 Protein, His tagged | HEK293F | Human | His |
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| CHD7-1634M | Recombinant Mouse CHD7 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| CHD7-1634M-B | Recombinant Mouse CHD7 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
CHD7 involved in several pathways and played different roles in them. We selected most pathways CHD7 participated on our site, such as Noncanonical Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Noncanonical Wnt signaling pathway | ROR2,CTHRC1 |
Protein Function
CHD7 has several biochemical functions, for example, ATP binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD7 itself. We selected most functions CHD7 had, and list some proteins which have the same functions with CHD7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | WSB1,RAP1A,MERTK,ADRB1,ZBTB6,TMIGD2,CD276,GRHL2,RGS8,COA5 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | KLF17,ASCL2,NKX6-1,ARID3B,TCF12,MAFA,FOSB,ZFP639,RFX8,JUNBB |
| helicase activity | SMARCAL1,GTF2F2,HELLS,MOV10B.2,SHPRH,HELZ2,DHX34,MCM9,MCM6L,GTF2F2B |
| chromatin binding | PRKAA1,HDAC3,TMPOA,KDM6B,NCAPD3,CBX7,SUPT5H,GM606,WHSC1,CREB3 |
| ATP binding | NLRP2,UCKL1A,BRAF,KIF1C,MAT1A,DDX58,ACACB,ACVR1C,BMPR1B,UBE2W |
Interacting Protein
CHD7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD7.
CHD8;CHD8;gli2_human_gene;jag1_human_gene;gli3_human_gene;mycn_human_gene;necd_human_gene;CBX4;NES;SNW1
Resources
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References
- Yamada, M; Sato, N; et al. Association of the Chromodomain Helicase DNA-Binding Protein 4 (CHD4) Missense Variation p.D140E with Cancer: Potential Interaction with Smoking. GENES CHROMOSOMES & CANCER 54:122-128(2015).
- Lee, SJ; Chae, JH; et al. Non-Homologous End Joining Repair Mechanism-Mediated Deletion of CHD7 Gene in a Patient with Typical CHARGE Syndrome. ANNALS OF LABORATORY MEDICINE 35:141-145(2015).
