CHD4

  • Official Full Name

    chromodomain helicase DNA binding protein 4

  • Overview

    Chromodomain-helicase-DNA-binding domain (CHD) proteins have been identified in a variety of organisms. This family of nine proteins is divided into three separate subfamilies: subfamily I (CHD1 and CHD2), subfamily II (CHD3 and CHD4), and subfamily III (

  • Synonyms

    CHD4;chromodomain helicase DNA binding protein 4;chromodomain-helicase-DNA-binding protein 4;Mi 2b;Mi2 BETA;CHD-4;ATP-dependent helicase CHD4;Mi-2 autoantigen 218 kDa protein;Mi-2b;Mi2-BETA;DKFZp686E06161

Recombinant Proteins

  • Human
  • Mouse
  • Insect Cell
  • Wheat Germ
  • Mammalian Cell
  • Baculovirus-Insect cells
  • E.coli
  • HEK293
  • His
  • Non
  • GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
CHD4-2434H Recombinant Human CHD4 protein, His-tagged Insect Cell Human His
CHD4-27065TH Recombinant Human CHD4 Wheat Germ Human Non 99 amino acids
CHD4-2793H Recombinant Human CHD4 protein, GST-tagged Wheat Germ Human GST 635-734 a.a.
CHD4-3379M Recombinant Mouse CHD4 Protein Mammalian Cell Mouse His
CHD4-346HCL Recombinant Human CHD4 cell lysate Human Non
CHD4-0338H Recombinant Human CHD4 Protein (Met1-Gln1912), C-His-tagged Baculovirus-Insect cells Human His Met1-Gln1912
CHD4-1180H Recombinant Human CHD4 Protein (1-239 aa), His-tagged E.coli Human His 1-239 aa
CHD4-1632M Recombinant Mouse CHD4 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
CHD4-1632M-B Recombinant Mouse CHD4 Protein Pre-coupled Magnetic Beads HEK293 Mouse
CHD4-5153H Recombinant Human CHD4 protein, His&His-tagged E.coli Human His 1-239aa
CHD4-772H Recombinant Human CHD4 Protein, His-tagged E.coli Human His Lys1681-Gln1912

    Involved Pathway

    CHD4 involved in several pathways and played different roles in them. We selected most pathways CHD4 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA Polymerase I Transcription Initiation RRN3,MBD3B,MTA2,MTA1,CHD4A,UBTF,MBD3A,GATAD2B,GATAD2AB,GATAD2A
    Chromatin organization SAP18,SMYD2,PADI2,KDM6AL,MBD3,SUDS3,PRDM16,ACTL6A,JADE1,SMARCA4
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription POLRMT,ZNF143B,MTERF,SNAPC5,SNAPC1B,GTF3AB,NFIA,BRF1,CBX3A,GATAD2B
    RNA Polymerase I Promoter Clearance TAF1C,GATAD2AB,CD3EAP,MTA3,MBD3B,GATAD2A,TAF1B,MBD3A,MTA2,RRN3
    RNA Polymerase I Transcription GATAD2B,UBTF,MBD3,MBD3B,PTRFB,MBD3A,PTRF,GATAD2AB,EFCAB11,TAF1B
    Gene Expression BRF1,VDRB,NR2F6,ZNF613,AGO3B,ZNF530,HNRNPA0,ZNF460,GATAD2A,ZNF563
    Chromatin modifying enzymes PHF15,KDM2A,ATXN7L3,BRD8,KDM6AL,DR1,RUVBL2,KDM4C,MBD3A,MEAF6
    HDACs deacetylate histones MTA1,SAP30L,SAP30,SUDS3,KDM1A,GATAD2AB,ANO9A,ARID4A,CHD4A,PHF21A

    Protein Function

    CHD4 has several biochemical functions, for example, ATP binding,ATP-dependent DNA helicase activity,DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD4 itself. We selected most functions CHD4 had, and list some proteins which have the same functions with CHD4. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to nucleosomal DNA binding ACTB,GATAD2B,HDAC2,MTA2,RBBP4,ACTL6A,SMARCB1,SMARCE1,SMARCC2,SMARCC1
    RNA polymerase II repressing transcription factor binding SP1,MTA2,GATA6,GTF2A2,BBS10,TCERG1,SIN3A,HDAC2,BBS5,MIXL1
    zinc ion binding CCS,SIRT3,SREK1IP1,SQSTM1,PAPPA2,TRIM8,BRF1B,ZDHHC18A,PHRF1,ADAM10B
    contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding MTA2,ACTB,RBBP4,SMARCA4,MBD3,SMARCB1,SMARCC2,GATAD2B,SMARCC1,ACTL6A
    contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding SMARCE1,SMARCC1,ACTB,MTA2,GATAD2B,ACTL6A,RBBP4,SMARCB1,HDAC1,SMARCC2
    ATP-dependent DNA helicase activity RTEL1,RUVBL2,CHD2,DDX3X,CHD1,FBXO18,CHST13,GTF2H4,RECQL,DHX9
    microtubule binding GABARAPL2,KIF22,CLIP1,KIF3C,FES,KATNAL2,MID1,VAPA,KIF3CB,JAKMIP2
    protein binding IGF2,PLXNB2,RSAD2,TRAM2,FAS,GRIK3,SLC1A5,PPARA,KPNA6,PPP5C
    ATP binding KIF2B,LIG3,CSNK1A1,ADRBK2,DHX58,RPS6KAL,PIK3R4,KIF18B,DCKL1B,FGFR4

    Interacting Protein

    CHD4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD4.

    HDAC1;E7;HDAC2;MYC;MTA2;MBD3;RNF8;NR4A1;TAF9;USP36

    Resources

    Research Area

    CHD Family

    References

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