CHD3
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Official Full Name
chromodomain helicase DNA binding protein 3 -
Overview
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] -
Synonyms
CHD3;chromodomain helicase DNA binding protein 3;ZFH;Mi-2a;Mi2-ALPHA;chromodomain-helicase-DNA-binding protein 3;hZFH;CHD-3;zinc finger helicase;ATP-dependent helicase CHD3;mi-2 autoantigen 240 kDa protein;zinc-finger helicase (Snf2-like)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CHD3-1214H | Recombinant Human CHD3 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| CHD3-450H | Recombinant Human CHD3 Protein, His-tagged | E.coli | Human | His | Cys1551~Phe1742 |
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| Chd3-451M | Recombinant Mouse Chd3 Protein, His-tagged | E.coli | Mouse | His | Ser1613~Ala1820 |
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| CHD3-1011H | Recombinant Human CHD3 Protein (Cys382-Phe573), N-His tagged | E.coli | Human | His | Cys382-Phe573 |
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Involved Pathway
CHD3 involved in several pathways and played different roles in them. We selected most pathways CHD3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
CHD3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CHD3 itself. We selected most functions CHD3 had, and list some proteins which have the same functions with CHD3. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
CHD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD3.
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References
- Thomas, RH; Zhang, LM; et al. CHD2 myoclonic encephalopathy is frequently associated with self-induced seizures. NEUROLOGY 84:951-958(2015).
- Hu, Y; Liu, XK; et al. CHD3 facilitates vRNP nuclear export by interacting with NES1 of influenza A virus NS2. CELLULAR AND MOLECULAR LIFE SCIENCES 72:971-982(2015).
