CDX1
-
Official Full Name
caudal type homeobox 1 -
Overview
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. -
Synonyms
CDX1;caudal type homeobox 1;caudal type homeo box transcription factor 1;homeobox protein CDX-1;caudal-type homeobox protein 1;caudal-type homeobox protein CDX1;caudal type homeobox transcription factor 1;MGC116915
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- His
- GST
- Non
- His&Fc&Avi
- His&T7
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CDX1-11074H | Recombinant Human CDX1, His-tagged | E.coli | Human | His | C-term-50a.a. | |
| CDX1-3682H | Recombinant Human CDX1 protein, GST-tagged | E.coli | Human | GST | 105-154 aa | |
| CDX1-1082H | Recombinant Human CDX1 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
|
| CDX1-27916TH | Recombinant Human CDX1 | Wheat Germ | Human | Non | 90 amino acids |
|
| CDX1-3241M | Recombinant Mouse CDX1 Protein | Mammalian Cell | Mouse | His |
|
|
| CDX1-6242C | Recombinant Chicken CDX1 | Mammalian Cell | Chicken | His |
|
|
| CDX1-7603HCL | Recombinant Human CDX1 293 Cell Lysate | HEK293 | Human | Non |
|
|
| CDX1-1551M | Recombinant Mouse CDX1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| CDX1-1551M-B | Recombinant Mouse CDX1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| CDX1-488H | Recombinant Human CDX1 Protein, T7-His-TEV-tagged | E.coli | Human | His&T7 |
|
Involved Pathway
CDX1 involved in several pathways and played different roles in them. We selected most pathways CDX1 participated on our site, such as Regulation of Wnt-mediated beta catenin signaling and target gene transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Wnt-mediated beta catenin signaling and target gene transcription | TCF4,KRT1,BCL9,TLE4,IGF2BP1,KCNIP4,ZCCHC12,SALL4,MYOG,T |
Protein Function
CDX1 has several biochemical functions, for example, RNA polymerase II distal enhancer sequence-specific DNA binding,protein binding,transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDX1 itself. We selected most functions CDX1 had, and list some proteins which have the same functions with CDX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | CUX1,HOXB5,BACH1,PROP1,POU4F1,FUBP1,SUB1,SIX3,NFE2L2,NFATC1 |
| protein binding | TRAF3IP2,NOS1AP,LYRM2,PDZD11,MICAL1,PPP2R5E,PHF10,TBCB,LDOC1,SYCE1 |
| RNA polymerase II distal enhancer sequence-specific DNA binding | RXRB,PBX3,GATA2,FLI1,MEOX2,REL,HOXB5,PROP1,HNRNPC,H2AFZ |
Interacting Protein
CDX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDX1.
CEBPA
Resources
Related Services
Related Products
References
- Ashley, N; Yeung, TM; et al. Stem Cell Differentiation and Lumen Formation in Colorectal Cancer Cell Lines and Primary Tumors. CANCER RESEARCH 73:5798-5809(2013).
- Naran, S; Abrams, P; et al. Bile Salts Differentially Sensitize Esophageal Squamous Cells to CD95 (Fas/Apo-1 Receptor) Mediated Apoptosis. JOURNAL OF SURGICAL RESEARCH 171:504-509(2011).
