CDK20
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Official Full Name
cyclin-dependent kinase 20 -
Overview
The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. -
Synonyms
P42;CCRK;CDCH;PNQALRE;cyclin-dependent kinase 20;CAK-kinase p42;OTTHUMP00000021607;OTTHUMP00000123392;OTTHUMP00000123393;CDK-activating kinase p42;cell cycle-related kinase;cell division protein kinase 20;cyclin-dependent protein kinase H;cyclin-kinase-activating kinase p42;CDK20
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- Rhesus macaque
- Insect Cell
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His&T7
- His
- Non
- His&Fc&Avi
Involved Pathway
CDK20 involved in several pathways and played different roles in them. We selected most pathways CDK20 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDK20 has several biochemical functions, for example, ATP binding,cyclin-dependent protein serine/threonine kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK20 itself. We selected most functions CDK20 had, and list some proteins which have the same functions with CDK20. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cyclin-dependent protein serine/threonine kinase activity | CDK12,CDK17,CDK14,CDKL3,CDKL1,NAT1,CDK13,MAK,CDK8,CDK5 |
| protein binding | C2orf88,ZFYVE20,RDM1,C5orf13,CRYAB,HIST1H2AK,RBM6,SR140,CCT4,GNB1 |
| ATP binding | ATP5B,JAK1,KITB,DHX36,KIF5AA,P2RX6,TRNT1,KCNJ1,CAMK2A,WRNIP1 |
Interacting Protein
CDK20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK20 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK20.
MAK;TRAFD1;ATP1A1;EEF2;NME2;POLR2B;PSMB2;SSR4;PSMC6;RBBP4;FKBP8;SMC1A;ERC1;PSMD1;NTPCR;FANCD2;CDK12;STUB1;NOP58
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References
- Ehrenschwender, M; Bittner, S; et al. XIAP-targeting drugs re-sensitize PIK3CA-mutated colorectal cancer cells for death receptor-induced apoptosis. CELL DEATH & DISEASE 5:-(2014).
- Hotowy, K; Wozniak, M; et al. Immunocytochemical studies on the nuclear ubiquitous casein and cyclin-dependent kinases substrate following 5-aminolevulinicacid-mediated photodynamic therapy on MCF-7 cells. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY 10:518-525(2013).
