CD1C
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Official Full Name
CD1c molecule -
Overview
CD1c, also known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in human. The CD1 molecules are type I glycoprotein with structural similarities to MHC class I and a non-covalent associated with beta 2 -microglobulin, belonging to Ig s -
Synonyms
CD1C;CD1c molecule;CD1, CD1c antigen , CD1C antigen, c polypeptide;T-cell surface glycoprotein CD1c;CD1C antigen, c polypeptide;cortical thymocyte antigen CD1C;differentiation antigen CD1-alpha-3;R7;CD1;CD1A;BDCA1
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- Human Cells
- Yeast
- Mammalian cells
- HEK293T
- His
- GST
- Non
- Fc
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CD1C involved in several pathways and played different roles in them. We selected most pathways CD1C participated on our site, such as Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hematopoietic cell lineage | IL7,ITGA3,GYPA,ITGA4,IL11RA,IL4R,HLA-DRB4,CR1,CD9,IL1R2 |
Protein Function
CD1C has several biochemical functions, for example, beta-2-microglobulin binding,endogenous lipid antigen binding,exogenous lipid antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD1C itself. We selected most functions CD1C had, and list some proteins which have the same functions with CD1C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-2-microglobulin binding | H2-Q10,HLA-A,CD1B,HLA-E,CD1d1,CD1A,CD1D2,HFE,CD1E,FCGRT |
| glycolipid binding | HSPA2,CLEC4F,GLTP,GLTPD2,PLEKHA8P1,GLTPD1,CPTP,PRRC2B,PLEKHA8 |
| endogenous lipid antigen binding | CD1B,CD1A,CD1D2,CD1E,CD1D,CD1d1 |
| exogenous lipid antigen binding | CD1E,CD1D2,CD1B,CD1A,CD1d1,CD1D |
| lipopeptide binding | CD1D2,CD1E,CD1B,CD1D,CD1d1,CD1A,TLR6 |
Interacting Protein
CD1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD1C here. Most of them are supplied by our site. Hope this information will be useful for your research of CD1C.
q81ky6_bacan;q81lj8_bacan
Resources
Research Area
Conventional/Classical Dendritic CellsLangerhans and Dermal Dendritic Cells
T Cell Antigen Recognition
Related Services
Related Products
References
- da Cunha, NP; Ghisleni, G; et al. Cytologic and immunocytochemical characterization of feline progressive histiocytosis. VETERINARY CLINICAL PATHOLOGY 43:428-436(2014).
- Liu, XB; Zhao, MD; et al. Toxoplasma gondii Infection of Decidual CD1c(+) Dendritic Cells Enhances Cytotoxicity of Decidual Natural Killer Cells. INFLAMMATION 37:1261-1270(2014).
