CC2D1A
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Official Full Name
coiled-coil and C2 domain containing 1A -
Overview
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3. -
Synonyms
CC2D1A;coiled-coil and C2 domain containing 1A;coiled-coil and C2 domain-containing protein 1A;FLJ20241;mental retardation;nonsyndromic;autosomal recessive;3;MRT3;Akt kinase-interacting protein 1;putative NFkB activating protein;FRE under dual
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CC2D1A involved in several pathways and played different roles in them. We selected most pathways CC2D1A participated on our site, such as SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CC2D1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SIDS Susceptibility Pathways | CDCA7L,SP3,LMX1B,TAC1,EN1,YBX1,POU2F2,DLX2,MAP2,MAZ |
Protein Function
CC2D1A has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CC2D1A itself. We selected most functions CC2D1A had, and list some proteins which have the same functions with CC2D1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | GCFC2,HELT,TBX15,ETS2,ASCL1,NFIL3-6,SNAI1,SKIL,HES1,ZFPM1 |
| signal transducer activity | OLFR154,GPR27,TAAR8B,FST,OR115-6,PLCD3A,PTH1RA,GNB3,GPR62,CCR12A |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | RUNX2,POU5F1,FOXQ2,FOXO3B,FOXB1B,BMPR1A,NFIB,SOX9A,SIM1A,NFIXB |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | BATF2,CC2D1B,KDM6A,NFIB,MYBL1,BATF3,E2F4,KCNA3,NRF1,ZNF695 |
Interacting Protein
CC2D1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CC2D1A here. Most of them are supplied by our site. Hope this information will be useful for your research of CC2D1A.
Dlg4;CDC37;MEX3C;Immt;Chmp4b;CHMP4B
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