CA8
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Official Full Name
carbonic anhydrase VIII -
Overview
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. -
Synonyms
CA8;carbonic anhydrase VIII;CALS;CARP;CAMRQ3;CA-VIII;CAR8;carbonic anhydrase 8;ENSMUSG00000041261;wdl;Cals1;AW546993;4 A1;4 7.7 cM;carbonic anhydrase-related protein;CA-RP VIII;carbonic anhydrase-like sequence 1;EC 4.2.1.1
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Rat
- E.coli
- Mouse
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
CA8 involved in several pathways and played different roles in them. We selected most pathways CA8 participated on our site, such as Nitrogen metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Nitrogen metabolism | CAR1,CAHZ,Car14,Car2,GLUD1B,CAR5A,CA4,GLUD1,CAR15,CAR7 |
Protein Function
CA8 has several biochemical functions, for example, carbonate dehydratase activity,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CA8 itself. We selected most functions CA8 had, and list some proteins which have the same functions with CA8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | RNF4,NR2C1,OAS2,HE1A,TRIM22,UBR5,CPA2,TRIM4,VPS8,RNF34A |
| carbonate dehydratase activity | CA5B,Car12,CA15C,Car2,CA2,CAR3,CA14,CAR15,CA5,CA4 |
| protein binding | ENOX1,WIBG,TRAPPC4,PNPT1,ANKRA2,KRT20,MCM2,ATP6V0A4,GLB1,KIAA0146 |
Interacting Protein
CA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA8.
TBX3;CRX;LNX1;SPDL1;HSD17B14;GGA2;MAGED1
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