Blvra
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Official Full Name
biliverdin reductase A -
Overview
Biliverdin reductases, such as BLVRA (EC 1.3.1.24), catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH (Komuro et al., 1996 -
Synonyms
BLVRA;biliverdin reductase A;BLVR;Biliverdin IX alpha reductase;BLVR A;BVR A;BVR;BVRA;Zinc metalloprotein;OTTHUMP00000159196;OTTHUMP00000207534;biliverdin-IX alpha-reductase
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- Non
- His
- His&T7
- His&Fc&Avi
- Myc&DDK
Involved Pathway
Blvra involved in several pathways and played different roles in them. We selected most pathways Blvra participated on our site, such as Porphyrin and chlorophyll metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Blvra were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Porphyrin and chlorophyll metabolism | UGT1A9,UROD,CPOX,PPOX,HMOX1,UGT1AB,HCCSA.1,ALAS1,GUSB,UGT1A3 |
Protein Function
Blvra has several biochemical functions, for example, biliverdin reductase activity,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Blvra itself. We selected most functions Blvra had, and list some proteins which have the same functions with Blvra. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ACBD3,SPC25,HIST1H3G,NTM,LRRC6,NOSTRIN,CD2,ZNF346,BDKRB1,RRAD |
| biliverdin reductase activity | BLVRB |
| zinc ion binding | ADAM20,TRIM12A,ZFP622,ADAM10A,P2RX4,PHF17,MLL1,SUV39H2,ZDHHC6,RNF166 |
Interacting Protein
Blvra has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Blvra here. Most of them are supplied by our site. Hope this information will be useful for your research of Blvra.
LNX1;Hmox1
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References
- Rucker, H; Amslinger, S; et al. Identification of heme oxygenase-1 stimulators by a convenient ELISA-based bilirubin quantification assay. FREE RADICAL BIOLOGY AND MEDICINE 78:135-146(2015).
- Muhsain, SNF; Lang, MA; et al. Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress. TOXICOLOGY AND APPLIED PHARMACOLOGY 282:77-89(2015).
