BMP15
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Official Full Name
bone morphogenetic protein 15 -
Overview
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming;growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and;differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular;development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause;of ovarian dysgenesis 2. -
Synonyms
BMP15;bone morphogenetic protein 15;GDF9B;BMP-15;GDF-9B;growth/differentiation factor 9B;ODG2;POF4
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Mouse
- Rat
- Sheep
- CHO
- E.coli
- Mammalian Cell
- HEK293
- Non
- His
- His&Fc&Avi
- His&Myc
Involved Pathway
BMP15 involved in several pathways and played different roles in them. We selected most pathways BMP15 participated on our site, such as Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ovarian steroidogenesis | INSR,INS,LHCGR,GDF9,Adcy4,INS1,HSD3B5,HSD17B7,CYP2J6,PLA2G4A |
Protein Function
BMP15 has several biochemical functions, for example, cytokine activity,growth factor activity,transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP15 itself. We selected most functions BMP15 had, and list some proteins which have the same functions with BMP15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| growth factor activity | HDGF,INHBAA,NTF7,MANF,FGF9,GPR19,CDNF,INHA,PRL2C3,FGF8A |
| transforming growth factor beta receptor binding | BMP2B,USP15,GDF11,INHBB,GDF6B,GDF9,GDF2,GDF1,INHA,BMP7B |
| cytokine activity | IL37,INHBB,IL17C,GDF2,Flt3l,TIMP1,MSTNA,OSTN,GDF15,Kitl |
Interacting Protein
BMP15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP15 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP15.
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References
- Lin, JY; Pitman-Crawford, JL; et al. Effects of species differences on oocyte regulation of granulosa cell function. REPRODUCTION 144:557-567(2012).
- Jin, M; Yu, YQ; et al. An update on primary ovarian insufficiency. SCIENCE CHINA-LIFE SCIENCES 55:677-686(2012).
