BDH1
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Official Full Name
3-hydroxybutyrate dehydrogenase, type 1 -
Overview
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. -
Synonyms
BDH1;3-hydroxybutyrate dehydrogenase, type 1;3 hydroxybutyrate dehydrogenase (heart, mitochondrial) , BDH;D-beta-hydroxybutyrate dehydrogenase, mitochondrial;SDR9C1;short chain dehydrogenase/reductase family 9C;member 1;3 hydroxybutyrate dehydrogenase (heart, mitochondrial);BDH;D beta hydroxybutyrate dehydrogenase, mitochondrial;OTTHUMP00000208056;OTTHUMP00000208057;OTTHUMP00000208058;OTTHUMP00000208059;(R)-3-hydroxybutyrate dehydrogenase;3-hydroxybutyrate dehydrogenase (heart, mitochondrial);short chain dehydrogenase/reductase
Recombinant Proteins
- Human
- Chicken
- Mouse
- Zebrafish
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
BDH1 involved in several pathways and played different roles in them. We selected most pathways BDH1 participated on our site, such as Synthesis and degradation of ketone bodies,Butanoate metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with BDH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Synthesis and degradation of ketone bodies | OXCT2B,OXCT2A,OXCT2,HMGCLL1,HMGCS1,HMGCS2,BDH2,OXCT1,ACAT2,OXCT1B |
| Metabolic pathways | TRIT1,THA1,IPMK,SMS,ATP5D,HADHB,CYP2R1,FUT6,CKM,PCK2 |
| Butanoate metabolism | OXCT1,ACSM2B,ACAT2,EHHADH,OXCT2A,ACSM2,HMGCLL1,GAD1B,ACAT1,ACSM3 |
Protein Function
BDH1 has several biochemical functions, for example, 3-hydroxybutyrate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BDH1 itself. We selected most functions BDH1 had, and list some proteins which have the same functions with BDH1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3-hydroxybutyrate dehydrogenase activity | BDH2 |
Interacting Protein
BDH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BDH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BDH1.
HDAC11;HDAC6
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