BCL2L13
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Official Full Name
BCL2-like 13 (apoptosis facilitator) -
Overview
Bcl-rambo shares the common structural characteristics with other members of the antiapoptotic Bcl-2 family members, but differs from them at its C-terminus, where a 250 amino acid sequence proceeds the membrance anchor region. It also differs from other -
Synonyms
BCL2L13;BCL2-like 13 (apoptosis facilitator);bcl-2-like protein 13;BCL RAMBO;MIL1;Protein Mil1;BCL-RAMBO;Bcl2-L-13
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Mus musculus
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- HEK293T
- E.coli expression system
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
BCL2L13 involved in several pathways and played different roles in them. We selected most pathways BCL2L13 participated on our site, such as Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL2L13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Legionellosis | HSPA1A,SAR1A,Casp3,TNF,IL18,EEF1A2,RAB1A,IL12A,EEF1A1,EEF1G |
Protein Function
BCL2L13 has several biochemical functions, for example, cysteine-type endopeptidase activator activity involved in apoptotic process,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL2L13 itself. We selected most functions BCL2L13 had, and list some proteins which have the same functions with BCL2L13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase activator activity involved in apoptotic process | APAF1,MAPK9,CTSH,NLRP12,NLRP1,CASP1,RPS27L,GNB2L1,CTSC,CARD8 |
| protein binding | ALDH1A2,NOD1,RNF24,C19orf73,MSRB3,KCTD1,EHD4,MTCH1,IFNAR2,GAGE1 |
Interacting Protein
BCL2L13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL2L13 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL2L13.
GABARAPL2;b2r9h7_human;VAMP4;VAMP3;BET1;TMEM128;TMUB2
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References
- Malik, D; Hsu, T; et al. Human Retinal Transmitochondrial Cybrids with J or H mtDNA Haplogroups Respond Differently to Ultraviolet Radiation: Implications for Retinal Diseases. PLOS ONE 9:-(2014).
- Jensen, SA; Calvert, AE; et al. Bcl2L13 is a ceramide synthase inhibitor in glioblastoma. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:5682-5687(2014).
