ATP1B2
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Official Full Name
ATPase, Na+/K+ transporting, beta 2 polypeptide -
Overview
Na+/K+-ATPase (fully Sodium-Potassium Adenosine Triphosphatase, also known as the Na+/K+ pump, sodium-potassium pump, or sodium pump, for short) is an enzyme (EC 3.6.3.9) located in the plasma membrane (to be specific, an electrogenic transmembrane ATPase) in all animals. -
Synonyms
AMOG;AT1B2;ATP1B2;ATPase Na+/K+ transporting beta 2 polypeptide;ATPB2;ATPB2S;MGC93648;Na+/K+ -ATPase beta 2 subunit;RATATPB2S;Sodium/potassium-dependent ATPase subunit beta-2;Sodium/potassium-transporting ATPase subunit beta-2;ATPase, Na+/K+ transporting, beta 2 polypeptide;adhesion molecule on glia;sodium/potassium-dependent ATPase beta-2 subunit;sodium/potassium-transporting ATPase beta-2 chain
Recombinant Proteins
- Human
- Mouse
- Rat
- Mus musculus
- Insect Cells
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- Human Cells
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ATP1B2 involved in several pathways and played different roles in them. We selected most pathways ATP1B2 participated on our site, such as cGMP-PKG signaling pathway,cAMP signaling pathway,Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP1B2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gastric acid secretion | ATP1A4,Car2,PRKACG,CALM2,ACTB,KCNE2,KCNJ10,CALM3,KCNK2,ITPR1 |
| Insulin secretion | GNA11,FXYD2,INS2,KCNN4,KCNMA1,GNAQ,Adcy4,STX1A,PRKCG,KCNMB4 |
| Carbohydrate digestion and absorption | ATP1A4,PIK3CD,HKDC1,GNAT3,AMY1B,G6PC3,SLC2A5,Amy1,PIK3R2,SLC37A4 |
| Endocrine and other factor-regulated calcium reabsorption | PTH1R,KLK1B3,GNAQ,PRKCB,ATP1B1,TRPV5,KLK1B5,ATP1A4,PRKACG,FXYD2 |
| Mineral absorption | MT1,SLC11A1,ATP7A,MT1E,ATP1B4,HEPH,STEAP2,ATP1A2,SLC9A3,MT1H |
| Proximal tubule bicarbonate reclamation | ATP1B3,PCK2,Car2,CA2,SLC4A4,ATP1B4,MDH1,SLC25A10,PCK1,GLS |
| cGMP-PKG signaling pathway | ATP2A2,ROCK1,NPR1,PPP3CA,NFATC3,ATP2B4,ATP1A2,SLC8A1,PPP3CB,ATP1B1 |
| Thyroid hormone signaling pathway | SLC16A2,MED12L,ATP1A3,ATP1A2,MED14,PDPK1,RXRB,MTOR,DIO1,PLCB1 |
| Salivary secretion | RYR3,PLCB3,CALM4,CALML3,ATP1A3,PRKACA,PMAP-36,Slc4a2,CALM3,Adcy4 |
Protein Function
ATP1B2 has several biochemical functions, for example, ATPase activator activity,ATPase binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP1B2 itself. We selected most functions ATP1B2 had, and list some proteins which have the same functions with ATP1B2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATPase activator activity | RAB4A,DNAJC15,DNAJB1,ATP1B1,DNAJC19,TOR1AIP1,AHSA1,AHSA1L,ATP1B3,DNAJB6 |
| sodium:potassium-exchanging ATPase activity | ATP1A3A,ATP1A2A,ATP1B3,ATP1A1A.5,ATP1A1,ATP1A1A.3,ATP1A4,ATP12A,FXYD2,ATP1A2 |
| protein binding | CA1,GAGE5,DCTN1,HIST1H4I,PPP2R5B,FAM168A,NXF1,TMSB4Y,MMS19,DYNC1H1 |
| contributes_to sodium:potassium-exchanging ATPase activity | ATP1A2,ATP1A1,ATP1B3,ATP1B1 |
| ATPase binding | SNX10,ATPIF1,FXYD4,NUFIP1,NKAIN1,ATP6V1E1,TOR1AIP2,SLC26A9,ESR1,PGR |
Interacting Protein
ATP1B2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP1B2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP1B2.
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