APLP1
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Official Full Name
amyloid beta (A4) precursor-like protein 1 -
Overview
Amyloid-like protein 1, also known as APLP1, is a protein that in humans is encoded by the APLP1 gene. APLP1 along with APLP2 are important modulators of glucose and insulin homeostasis. -
Synonyms
APLP1;amyloid beta (A4) precursor-like protein 1;amyloid-like protein 1;amyloid precursor like protein 1;amyloid like protein 1;APLP;APLP-1;amyloid precursor-like protein 1
Recombinant Proteins
- Human
- Mouse
- Mus musculus
- Human Cells
- E.coli
- Mammalian Cells
- E.Coli/Yeast
- Wheat Germ
- HEK293
- Non
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| APLP1-350H | Recombinant Human APLP1, His tagged | Human Cells | Human | Non | 1-580 a.a. | |
| APLP1-9745H | Recombinant Human APLP1, GST-tagged | E.coli | Human | GST | 55-341a.a. | |
| APLP1-3718H | Recombinant Human APLP1 protein, His-tagged | E.coli | Human | His | 55-341 aa | |
| APLP1-394H | Recombinant Human APLP1 Protein, His-tagged | E.coli | Human | His | Arg62~Phe202 | |
| APLP1-1776M | Recombinant Mouse APLP1 Protein | Mammalian Cells | Mouse | His |
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| APLP1-26119TH | Recombinant Human APLP1, His-tagged | E.coli | Human | His | 274-651 a.a. |
|
| Aplp1-3443M | Recombinant Mouse Aplp1, His-tagged | E.Coli/Yeast | Mouse | His | 654 |
|
| APLP1-687H | Recombinant Human APLP1 protein, GST-tagged | Wheat Germ | Human | GST |
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| APLP1-1031HCL | Recombinant Human APLP1 cell lysate | Human Cells | Human | Non |
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| APLP1-1102H | Recombinant Human APLP1 protein(Met1-Glu580), His-tagged | HEK293 | Human | His | Met1-Glu580 |
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| Aplp1-295M | Recombinant Mouse Aplp1 Protein, His-tagged | HEK293 | Mouse | His | Met1-Glu584 |
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| APLP1-623M | Recombinant Mouse APLP1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| APLP1-623M-B | Recombinant Mouse APLP1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| APLP1-63H | Recombinant Human APLP1 Protein, His-tagged | Human Cells | Human | His | Gly42-Pro212 |
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| RFL-30829MF | Recombinant Full Length Mouse Amyloid-Like Protein 1(Aplp1) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length of Mature Protein (38-653) |
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| RFL-35884HF | Recombinant Full Length Human Amyloid-Like Protein 1(Aplp1) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length of Mature Protein (39-650) |
|
Involved Pathway
APLP1 involved in several pathways and played different roles in them. We selected most pathways APLP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APLP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APLP1 has several biochemical functions, for example, alpha-2A adrenergic receptor binding,alpha-2B adrenergic receptor binding,alpha-2C adrenergic receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APLP1 itself. We selected most functions APLP1 had, and list some proteins which have the same functions with APLP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alpha-2A adrenergic receptor binding | ADRB1,ADRBK1,UCHL1,ADRA2C |
| heparin binding | GPNMB,APP,FGFR1,SOST,Itgam&Itgb2,SELL,APOE,C6orf25,MPO,RPL22 |
| identical protein binding | GLUL,IGF1R,SSNA1,SETX,IL12B,CEACAM5,BIRC5,ITGB3,S100B,GRIN3A |
| protein binding | FCN1,TFAP4,FAM156A,ZKSCAN4,FOXL2,LBR,TNFAIP8L1,HIST1H1A,CASP7,WDFY3 |
| alpha-2C adrenergic receptor binding | ADRA2A |
| transition metal ion binding | APPA,APP,HRSP12,APLP2,APPB |
Interacting Protein
APLP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APLP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of APLP1.
TK1;TSC22D1;APP;APLP2;ZNF24;CNTN5;CNTN4;MED12;CNTN3;Tom1;FOS
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References
- Shi, M; Movius, J; et al. Cerebrospinal Fluid Peptides as Potential Parkinson Disease Biomarkers: A Staged Pipeline for Discovery and Validation. MOLECULAR & CELLULAR PROTEOMICS 14:544-555(2015).
- Sano, S; Tagami, S; et al. Absolute Quantitation of Low Abundance Plasma APL1 beta peptides at Sub-fmol/mL Level by SRM/MRM without Immunoaffinity Enrichment. JOURNAL OF PROTEOME RESEARCH 13:1012-1020(2014).
