AP4B1
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Official Full Name
adaptor-related protein complex 4, beta 1 subunit -
Overview
The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1; MIM 607244), a medium chain, mu-4 (AP4M1; MIM 602296), and a small chain, sigma-4 (AP4S1; MIM 607243). -
Synonyms
AP4B1;adaptor-related protein complex 4, beta 1 subunit;AP-4 complex subunit beta-1;beta 4 subunit of AP 4;BETA 4;Adapter related protein complex 4 beta 1 subunit;AP 4 adapter complex subunit beta;AP 4 complex subunit beta 1;Beta subunit of AP 4;beta4-adaptin;OTTHUMP00000013725;OTTHUMP00000013726;OTTHUMP00000013730;beta subunit of AP-4;beta 4 subunit of AP-4;AP-4 adapter complex subunit beta;adapter-related protein complex 4 subunit beta-1;CPSQ5;BETA-4
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AP4B1-9725H | Recombinant Human AP4B1, GST-tagged | E.coli | Human | GST | 1-351a.a. | |
| AP4B1-10662Z | Recombinant Zebrafish AP4B1 | Mammalian Cells | Zebrafish | His |
|
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| AP4B1-2606C | Recombinant Chicken AP4B1 | Mammalian Cells | Chicken | His |
|
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| AP4B1-661H | Recombinant Human AP4B1 protein, GST-tagged | Wheat Germ | Human | GST |
|
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| AP4B1-8806HCL | Recombinant Human AP4B1 293 Cell Lysate | HEK293 | Human | Non |
|
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| AP4B1-1138HF | Recombinant Full Length Human AP4B1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 739 amino acids |
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| AP4B1-194H | Recombinant Human AP4B1 Protein, His-tagged | E.coli | Human | His | Met1-Arg276 |
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| Ap4b1-195M | Recombinant Mouse Ap4b1 Protein, His-tagged | E.coli | Mouse | His | Met1-Ile261 |
|
Involved Pathway
AP4B1 involved in several pathways and played different roles in them. We selected most pathways AP4B1 participated on our site, such as Clathrin derived vesicle budding,Golgi Associated Vesicle Biogenesis,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP4B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| trans-Golgi Network Vesicle Budding | BLOC1S1,TPD52,BLOC1S3,PLDN,SNX9A,SNAPIN,TGOLN2,CLVS1,CLINT1,CNO |
| Clathrin derived vesicle budding | AP1B1,CLTC,BLOC1S1,DTNBP1B,SNX9A,TGOLN2,BLOC1S3,FTH1A,PPIAL4A,CTSZ |
| Lysosome Vesicle Biogenesis | BLOC1S1,CTSZ,CLVS1,CLVS2,DNASE2,AP1S3A |
| Membrane Trafficking | TRAPPC2,COPG,SEC22C,HIP1RB,GAK,SEC22A,PREB,MIA3,EXOC8,LMAN2L |
| Vesicle-mediated transport | HIP1RB,DNASE2,CLINT1,SNX9B,GJA5,SNAPIN,PICALMB,CNO,CTAGE5,GJB3 |
| Golgi Associated Vesicle Biogenesis | GAK,SNX9A,BLOC1S6,PICALMB,AP1S1,CPD,NAPAB,AP3S1,FTH1A,HIP1R |
| Lysosome | LAPTM5,NEU1,GLA,AP4M1,ATP6V0C,ASAH1A,FUCA1,CTSLA,GLB1,GALCB |
Protein Function
AP4B1 has several biochemical functions, for example, protein binding,protein transporter activity,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP4B1 itself. We selected most functions AP4B1 had, and list some proteins which have the same functions with AP4B1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SPRY2,CCR3,ASCL1,SPEF1,MAP3K3,SLX1B,WDR74,MUSK,MARK3,STATH |
| protein transporter activity | XPO6,KPNA6,SOSTDC1B,AP4S1,AP1S1,RAMP1,AP1G1,TIMM10,AP1G2,DSCR3 |
| transporter activity | FLVCR1,MFSD9,SLCO1A6,SLC13A1,CRABP1,ABCC1,TMEM184B,SLC2A15B,SLC6A20B,RLBP1A |
Interacting Protein
AP4B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP4B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP4B1.
ZNF576;FIBP;MYC;AP4E1;AP4S1
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