AOAH
-
Official Full Name
acyloxyacyl hydrolase (neutrophil) -
Overview
This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described. -
Synonyms
AOAH;acyloxyacyl hydrolase (neutrophil);acyloxyacyl hydrolase
Recombinant Proteins
- Human
- Mouse
- Rabbit
- E.coli
- Wheat Germ
- Mammalian Cell
- E.Coli or Yeast
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian cells
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
- Flag
Involved Pathway
AOAH involved in several pathways and played different roles in them. We selected most pathways AOAH participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AOAH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
AOAH has several biochemical functions, for example, acyloxyacyl hydrolase activity,catalytic activity,lipoprotein lipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AOAH itself. We selected most functions AOAH had, and list some proteins which have the same functions with AOAH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| catalytic activity | LDHBB,ACSL4B,ACAA1A,CDYL,SLC27A1A,PKMA,SULF2A,SPTLC2B,SLC3A2,GTF2F2B |
| lipoprotein lipase activity | LPL,LIPG |
Interacting Protein
AOAH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AOAH here. Most of them are supplied by our site. Hope this information will be useful for your research of AOAH.
IGHG1
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References
- Shao, BM; Kitchens, RL; et al. Prolonged Hepatomegaly in Mice That Cannot Inactivate Bacterial Endotoxin. HEPATOLOGY 54:1051-1062(2011).
- Ojogun, N; Kuang, TY; et al. Overproduction of Acyloxyacyl Hydrolase by Macrophages and Dendritic Cells Prevents Prolonged Reactions to Bacterial Lipopolysaccharide In Vivo. JOURNAL OF INFECTIOUS DISEASES 200:1685-1693(2009).
