ANTXR2
-
Official Full Name
anthrax toxin receptor 2 -
Overview
This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ANTXR2;anthrax toxin receptor 2;capillary morphogenesis protein 2;CMG 2;CMG2;FLJ31074;ISH;JHF;MGC111533;MGC45856;2310046B19Rik;ANTR2_HUMAN;AW561899;Capillary morphogenesis gene 2 protein;CMG-2
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- C-His
- E.Coli/Yeast
- Insect Cells
- Human Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Fc
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ANTXR2 involved in several pathways and played different roles in them. We selected most pathways ANTXR2 participated on our site, such as Cellular roles of Anthrax toxin,Disease,Infectious disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANTXR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Uptake and actions of bacterial toxins | ANTXR1,PDCD6IP,SYT2 |
| Cellular roles of Anthrax toxin | ANTXR1,DEFA1 |
| Disease | CCDC167,LTF,AP2A1,CCR5,gag,JAG1,CPSF6,FDX1L,PPIAL4A,CTDP1 |
| Infectious disease | KPNA4,NMT2,TAF1L,APOBEC3G,AP1S1,KPNA3,CPSF4,PDCD6IP,CHMP4B,CCDC167 |
| Uptake and function of anthrax toxins | ANTXR1 |
Protein Function
ANTXR2 has several biochemical functions, for example, metal ion binding,protein binding,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANTXR2 itself. We selected most functions ANTXR2 had, and list some proteins which have the same functions with ANTXR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FERD3L,ZNF274,FATE1,RARG,EDARADD,PIR,FBXW11,SNX31,SPANXA1,DLG4 |
| metal ion binding | EGR1,NLN,ZNF658,NPTXR,GLIS2,ECE2,ZNRF2B,BCL11AA,CHN2,SMYD1 |
| receptor activity | CD93,PLXNA1,PVRL1A,EPHB6,NLGN4B,LILRB4,NOTCH1B,CD226,TIGIT,CD40 |
Interacting Protein
ANTXR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANTXR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANTXR2.
pagA;LRP6;SMAD2
Resources
Related Services
Related Products
References
- Sharma, S; Thomas, D; et al. Efficient Neutralization of Antibody-Resistant Forms of Anthrax Toxin by a Soluble Receptor Decoy Inhibitor. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 53:1210-1212(2009).
- Manayani, DJ; Thomas, D; et al. A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. PLOS PATHOGENS 3:1422-1431(2007).
- Mabry, R; Brasky, K; et al. Detection of anthrax toxin in the serum of animals infected with Bacillus anthracis by using engineered immunoassays. CLINICAL AND VACCINE IMMUNOLOGY 13:671-677(2006).
