AMY2A
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Official Full Name
amylase, alpha 2A (pancreatic) -
Overview
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. -
Synonyms
AMY2A;amylase, alpha 2A (pancreatic);AMY2, amylase, alpha 2A;pancreatic;pancreatic alpha-amylase;1,4 alpha D glucan glucanohydrolase;Alpha amylase;AMY2;AMY2B;Amylase, alpha 2A;Amylase, pancreatic, A;Glycogenase;PA;alpha-amylase;OTTHUMP00000012694;found in the pancreas;pancreatic amylase 2A;pancreatic amylase alpha 2A;amylase, pancreatic, alpha-2A;1,4-alpha-D-glucan glucanohydrolase
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Cynomolgus
- Rhesus macaque
- E.coli
- Mammalian Cell
- Human Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- Pancreas
- His
- Fc
- GST
- His&T7
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AMY2A-3520H | Recombinant Human AMY2A protein, His-tagged | E.coli | Human | His | 162-511 aa | |
| AMY2A-1116C | Recombinant Chicken AMY2A | Mammalian Cell | Chicken | His |
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| AMY2A-12252Z | Recombinant Zebrafish AMY2A | Mammalian Cell | Zebrafish | His |
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| AMY2A-194C | Recombinant Cynomolgus AMY2A, Fc-tagged | Human Cell | Cynomolgus | Fc | Met1-Leu511 |
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| AMY2A-535H | Recombinant Human AMY2A protein, GST-tagged | Wheat Germ | Human | GST |
|
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| AMY2A-56C | Recombinant Cynomolgus AMY2A, His tagged | Human Cell | Cynomolgus | Fc | 1-511 a.a. |
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| AMY2A-6978H | Recombinant Human AMY2A protein, His & T7-tagged | E.coli | Human | His&T7 | Asp188~Val432 |
|
| AMY2A-8569H | Recombinant Human AMY2A protein(Met1-Leu511), His-tagged | HEK293 | Human | His | 1-511 a.a. |
|
| AMY2A-001CCL | Recombinant Cynomolgus AMY2A cell lysate | Human Cell | Cynomolgus | Non |
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| AMY2A-1351HCL | Recombinant Human AMY2A cell lysate | Human Cell | Human | Non |
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| AMY2A-0555H | Recombinant Human AMY2A Protein (Asp188-Val432), N-His-tagged | E.coli | Human | His | Asp188-Val432 |
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| AMY2A-1031HF | Recombinant Full Length Human AMY2A Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 511 amino acids |
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| AMY2A-16H | Human alpha-amylase Reference Standard | Human | Non |
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| AMY2A-538R | Recombinant Rhesus AMY2A protein, His-tagged | HEK293 | Rhesus macaque | His | Met1-Leu511 |
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| AMY2A-697R | Recombinant Rhesus AMY2A protein, hFc-tagged | HEK293 | Rhesus macaque | Fc | Met1-Leu511 |
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| AMY2A-8353H | Native Human AMY2A | Pancreas | Human | Non |
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Involved Pathway
AMY2A involved in several pathways and played different roles in them. We selected most pathways AMY2A participated on our site, such as Starch and sucrose metabolism,Metabolic pathways,Pancreatic secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMY2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ATP5E,AMY1A,ST6GALNAC5,CKMA,ATP6V1E1,COQ6,ATIC,AMY2A3,PPT1,PLD4 |
| Carbohydrate digestion and absorption | AKT2,G6PC,PIK3CA,ATP1B1,PRKCB,TAS1R3,AKT1,Amy1,GNAT3,PIK3R1 |
| Pancreatic secretion | RAB27B,PLA2G3,ITPR3,PRSS3,CLCA4,CELA3B,AMY2B,RAC1,RAP1A,ATP1A1 |
| Starch and sucrose metabolism | GPI1,GANC,AGL,SI,GAA,UGT2A1,ENPP1,GPIB,G6PCA.1,UXS1 |
Protein Function
AMY2A has several biochemical functions, for example, alpha-amylase activity,calcium ion binding,chloride ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMY2A itself. We selected most functions AMY2A had, and list some proteins which have the same functions with AMY2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | GUCA1B,DSG1,CCBE1,NECAB3,PDCD6,PCDH1G1,CAPSL,PCDH7,EPDR1,ESYT2 |
| chloride ion binding | NLGN4X,SLC22A6,Amy1,CTSC,ACE |
| alpha-amylase activity | AMY1A,AMY2B,AMY1B,AMY2A5,AMY2A4,Amy1,AMY2A2,AMY2A3 |
Interacting Protein
AMY2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMY2A here. Most of them are supplied by our site. Hope this information will be useful for your research of AMY2A.
TRIAP1;IGF1R;CDK6
Resources
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References
- TSUNODA, Y; OWYANG, C; et al. THE REGULATORY SITE OF FUNCTIONAL GTP-BINDING PROTEIN-COUPLED TO THE HIGH-AFFINITY CHOLECYSTOKININ RECEPTOR AND PHOSPHOLIPASE A(2) PATHWAY IS ON THE G(BETA) SUBUNIT OF G(Q) PROTEIN IN PANCREATIC ACINI. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 211:648-655(1995).
