AMHR2
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Official Full Name
anti-Mullerian hormone receptor, type II -
Overview
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
AMHR2;anti-Mullerian hormone receptor, type II;anti-Muellerian hormone type-2 receptor;MISR2;MISRII;M?llerian inhibiting substance type II receptor;AMH type II receptor;AMHR2_HUMAN;Anti-Muellerian hormone type II receptor;MGC141312;MIS type II receptor;MRII;Muellerian hormone type 2 receptor;Muellerian hormone type II receptor;Mullerian hormone receptor type II;OTTHUMP00000242707;OTTHUMP00000242708;OTTHUMP00000242709;Mullerian inhibiting substance type II receptor;AMHR
Recombinant Proteins
- Rat
- Human
- Mouse
- Cynomolgus
- Mammalian Cell
- Human Cell
- Mammalian cells
- HEK293
- Wheat Germ
- Spodoptera Frugiperda
- Insect Cell
- In Vitro Cell Free System
- HEK293T
- His
- Fc
- Non
- His&Avi
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
AMHR2 involved in several pathways and played different roles in them. We selected most pathways AMHR2 participated on our site, such as Cytokine-cytokine receptor interaction,TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMHR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TGF-beta signaling pathway | BMPR2,RHOA,RHOAD,MYCB,BAMBI,BMP2,PITX2,ID1,GDF7,BMP6 |
| Cytokine-cytokine receptor interaction | IFNA8,IFNA21,KITLG,CSF2RB,IFNG,Pdgfa&Pdgfb,IL17A,IL2RGB,CCL13,GM13306 |
Protein Function
AMHR2 has several biochemical functions, for example, ATP binding,anti-Mullerian hormone receptor activity,hormone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMHR2 itself. We selected most functions AMHR2 had, and list some proteins which have the same functions with AMHR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZNF563,RORCB,ZNF718,RNF207,RREB1,HMOX2A,NR5A1B,CAR13,ZNF613,FTR82 |
| transforming growth factor beta receptor activity, type II | TGFBR2 |
| hormone binding | CRYM,ADIPOR1B,NPR1,MC5R,MTNR1A,ADIPOR1A,NPR3,MC1R,NPR2,TTR |
| receptor signaling protein serine/threonine kinase activity | BMPR2A,PAK2B,BMPR2,OXSR1B,ACVR2AA,ACVR1C,BMPR1AB,ACVR2A,TGFBR1A,PANK1A |
| ATP binding | MAPK8B,MOS,CKBB,SMC4,KIF15,ABCG2,ATP4A,STK32C,SRPK2,TYK2 |
| receptor activity | PAQR5,NRXN1,FOLR1,LILRA2,SLC20A1,F2RL1.2,TLR4,VMN1R44,IL10RA,OPN1SW |
| protein binding | RPS3,KRT1,Siglec1,KIR2DL3,APOBEC2B,MATK,NRP1B,HTR3C,LILRA4,PLXNC1 |
Interacting Protein
AMHR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMHR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AMHR2.
HSP90AB1;HSP90AA1;CDC37;Hacd3
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