ALDOC
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Official Full Name
aldolase C, fructose-bisphosphate -
Overview
This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. -
Synonyms
ALDOC;aldolase C, fructose-bisphosphate;fructose-bisphosphate aldolase C;aldolase 3;fructoaldolase C;brain-type aldolase;fructose-1,6-biphosphate triosephosphate lyase;ALDC
Recombinant Proteins
- Human
- Chicken
- Mouse
- Rat
- E.coli
- HEK293
- Mammalian Cell
- Wheat Germ
- Mammalian cells
- In Vitro Cell Free System
- Yeast
- Insect Cell
- HEK293T
- His
- Myc&DDK
- GST
- Non
- His&Fc&Avi
- Flag
Involved Pathway
ALDOC involved in several pathways and played different roles in them. We selected most pathways ALDOC participated on our site, such as Glycolysis / Gluconeogenesis,Pentose phosphate pathway,Fructose and mannose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDOC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biosynthesis of amino acids | GLULB,PGAM1B,THA1,ALDOA,PFKM,CBSA,TKTL2,ALDOAA,IDH3B,TAT |
| Carbon metabolism | ECHS1,PGK1,PDHB,ACSS2,DAK,PCCA,SDS,G6PD,ALDOCB,HKDC1 |
| Metabolic pathways | PI4K2A,ATP5IB,PLA2G12B,MTHFD2,PCCA,LTA4H,SCP2A,RDH11,B3GNT5B,GALNT18 |
| Fructose and mannose metabolism | ENOSF1,FBP1B,AKR1B10,C12orf5,AKR1B7,PFKFB3,PFKFB2A,FPGT,Akr1b3,PFKFB2 |
| Pentose phosphate pathway | TKTB,G6PD,RBKS,TALDO1,PGLS,RPIA,PRPS2,FBP2,FBP1,PGM2 |
| Glycolysis / Gluconeogenesis | PGAM1A,ALDOCB,PKM,PKMB,ALDH2.1,MINPP1,PGK2,PGAM2,PCK1,DLDH |
Protein Function
ALDOC has several biochemical functions, for example, cytoskeletal protein binding,fructose-bisphosphate aldolase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDOC itself. We selected most functions ALDOC had, and list some proteins which have the same functions with ALDOC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytoskeletal protein binding | SLC8A1,EPB41L4A,TNNT2A,PKD2,ALDOB,FARP2,EPB41L4B,LIN7C,Fert2,FABP3 |
| protein binding | TXNRD2,KLF3,TGFBI,PDPK1,KRT38,METTL21C,GSTO1,RAPGEF6,MBIP,MRPS16 |
| fructose-bisphosphate aldolase activity | ALDOAB,ALDOCA,ALDOB,ALDOCB,ALDOA,ALDOAA |
Interacting Protein
ALDOC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALDOC here. Most of them are supplied by our site. Hope this information will be useful for your research of ALDOC.
ALDOA;LNX1;saicar;PKM;MAP2K3;SQLE;ere_dna;ALDOA;HTT;GABARAPL1
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