AGFG2
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Official Full Name
ArfGAP with FG repeats 2 -
Overview
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. The 3 UTR of this gene contains an insulin receptor substrate 3-like pseudogene. -
Synonyms
AGFG2;ArfGAP with FG repeats 2;HIV 1 Rev binding protein like , HRBL;arf-GAP domain and FG repeats-containing protein 2;RABR;AGFG2_HUMAN;Arf GAP domain and FG repeats containing protein 2;HIV-1 Rev-binding protein-like protein;HIV1 Rev binding protein like protein;HRBL;Nucleoporin;RAB-R;Rev/Rex activation domain-binding protein related;OTTHUMP00000209085;Rev/Rex activation domain binding protein-related
Recombinant Proteins
- Human
- Mouse
- E.Coli or Yeast
- Wheat Germ
- HEK293
- Mammalian Cell
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Myc&DDK
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AGFG2-3613H | Recombinant Human AGFG2, His-tagged | E.Coli or Yeast | Human | His | 481 |
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| AGFG2-5030H | Recombinant Human AGFG2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| AGFG2-530H | Recombinant Human AGFG2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| AGFG2-674H | Recombinant Human AGFG2 | Mammalian Cell | Human | His |
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| AGFG2-8981HCL | Recombinant Human AGFG2 293 Cell Lysate | HEK293 | Human | Non |
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| Agfg2-1553M | Recombinant Mouse Agfg2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| AGFG2-2440H | Recombinant Human AGFG2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| AGFG2-2440H-B | Recombinant Human AGFG2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| AGFG2-3657HF | Recombinant Full Length Human AGFG2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 155 amino acids |
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Involved Pathway
AGFG2 involved in several pathways and played different roles in them. We selected most pathways AGFG2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AGFG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
AGFG2 has several biochemical functions, for example, GTPase activator activity,metal ion binding,molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by AGFG2 itself. We selected most functions AGFG2 had, and list some proteins which have the same functions with AGFG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | MAGEA9,DEFA25,HIST2H2AA4,MFSD6B,FANCE,TTC39A,TMEM88A,MS4A13,FAM187A,MUP19 |
| metal ion binding | ZNF483,ZNF654,SMAD7,CYP2X9,OTUD7A,TMPPE,ACAP1,EYA1,RUFY2,G2E3 |
| GTPase activator activity | ARHGAP44,ARHGEF1,ARHGAP18,TBC1D2B,RALGAPA2,STARD13,EVI5L,ARHGAP19,RGS9A,TBC1D9B |
Interacting Protein
AGFG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGFG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGFG2.
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