ZMYM2
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Official Full Name
zinc finger, MYM-type 2 -
Overview
The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010] -
Synonyms
ZMYM2;zinc finger, MYM-type 2;FIM;MYM;RAMP;SCLL;ZNF198;zinc finger MYM-type protein 2;zinc finger protein 198;fused in myeloproliferative disorders protein;rearranged in an atypical myeloproliferative disorder
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Mammalian Cells
- HEK293
- E.coli
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZMYM2-19200M | Recombinant Mouse ZMYM2 Protein | Mammalian Cells | Mouse | His |
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| ZMYM2-5299R | Recombinant Rhesus monkey ZMYM2 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| ZMYM2-10391M | Recombinant Mouse ZMYM2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ZMYM2-10391M-B | Recombinant Mouse ZMYM2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ZMYM2-5112R | Recombinant Rhesus Macaque ZMYM2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ZMYM2-5112R-B | Recombinant Rhesus Macaque ZMYM2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| ZMYM2-5744H | Recombinant Human ZMYM2 protein, GST-tagged | E.coli | Human | GST | 423-466a.a. |
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Involved Pathway
ZMYM2 involved in several pathways and played different roles in them. We selected most pathways ZMYM2 participated on our site, such as PluriNetWork, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZMYM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PluriNetWork | IPO7,XPO4,ZSCAN10,KLF5,ZFP143,ZFP57,SMARCC1,RCOR2,SALL3 |
Protein Function
ZMYM2 has several biochemical functions, for example, metal ion binding,protein binding,ubiquitin conjugating enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZMYM2 itself. We selected most functions ZMYM2 had, and list some proteins which have the same functions with ZMYM2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZFP410,LMO7A,ISG20,Scd1,LMX1BB,CYP3A25,ACVRL1,ZNF726,PVALB2,ADI1 |
| ubiquitin conjugating enzyme binding | DCUN1D2,FOXL2,RNF144A,ARIH2,ANKIB1A,RNF144B,DCUN1D5,ARIH1,ANKIB1,RNF144AA |
| zinc ion binding | ERAP1,CIZ1,MMP15,LMO4A,USP39,MECR,NAPEPLD,PHF21B,KAT7A,MANEA |
| protein binding | POLB,S100A9,PIGS,RBPJ,ETNK1,NOL3,SKA1,SLC35F6,AGTRAP,GPN3 |
Interacting Protein
ZMYM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZMYM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZMYM2.
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References
- Guzzo, CM; Ringel, A; et al. Characterization of the SUMO-Binding Activity of the Myeloproliferative and Mental Retardation (MYM)-Type Zinc Fingers in ZNF261 and ZNF198. PLOS ONE 9:-(2014).
- Nam, SW; Park, KC; et al. Identification of Zinc Finger, MYM-type 2 (ZMYM2) as a regulator of sorafenib resistance in hepatocellular carcinoma cell lines. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 29:633-639(2014).
