ZFP36L1

  • Official Full Name

    zinc finger protein 36, C3H type-like 1

  • Overview

    This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    ZFP36L1;zinc finger protein 36, C3H type-like 1;BRF1, zinc finger protein, C3H type, 36 like 1;zinc finger protein 36, C3H1 type-like 1;Berg36;cMG1;ERF1;RNF162B;TIS11B;EGF-response factor 1;butyrate response factor 1;early response factor Berg

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • GST
  • His&GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ZFP36L1-3802H Recombinant Human ZFP36L1, GST-tagged E.coli Human GST 1-338aa
ZFP36L1-090H Recombinant Human ZFP36L1 Protein, GST-HIS-tagged E.coli Human His&GST
ZFP36L1-18910M Recombinant Mouse ZFP36L1 Protein Mammalian Cells Mouse His
ZFP36L1-3801H Recombinant Human ZFP36L1 protein, GST-tagged Wheat Germ Human GST 1-108 a.a.
ZFP36L1-6682R Recombinant Rat ZFP36L1 Protein Mammalian Cells Rat His
ZFP36L1-180HCL Recombinant Human ZFP36L1 293 Cell Lysate HEK293 Human Non
ZFP36L1-10346M Recombinant Mouse ZFP36L1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ZFP36L1-10346M-B Recombinant Mouse ZFP36L1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
ZFP36L1-6329R Recombinant Rat ZFP36L1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
ZFP36L1-6329R-B Recombinant Rat ZFP36L1 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    ZFP36L1 involved in several pathways and played different roles in them. We selected most pathways ZFP36L1 participated on our site, such as Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA,Gene Expression,Regulation of mRNA stability by proteins that bind AU-rich elements, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZFP36L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Validated targets of C-MYC transcriptional repression GFI1,NDRG1,LGALS1,TMEFF2,S100A7,MXD4,CSDE1,SFXN3,CLU,DNTT
    Regulation of mRNA stability by proteins that bind AU-rich elements ANP32A,HNRNPD,SETB,ELAVL1,KHSRP,SET,HUG,ZFP36L1B,ZFP36L1A,TNPO1
    Gene Expression UBTF,ALKBH8,ESRRA,ZNF692,MTA2,FKBP6,ZNF750,SURF1,TRMT112,KARS
    Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA EXOSC8,DCP2,ZFP36L1A,ZFP36L1B,MAPKAPK2B

    Protein Function

    ZFP36L1 has several biochemical functions, for example, AU-rich element binding,DNA binding,mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZFP36L1 itself. We selected most functions ZFP36L1 had, and list some proteins which have the same functions with ZFP36L1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding NT5C2,SMPDL3A,TMED10,CSPG5,DHX15,TMEM31,PLAA,USP18,CHMP4A,ANKRD54
    DNA binding ZFP30,ZNF266,TRERF1,RAD51C,SOX19A,NKX2.9,HIST1H2AB,CDAN1,IRX5B,ZFP382
    metal ion binding GDE1,NOTCH1A,LHX2B,MKNK2,ESYT1,TNNC1,MCCC1,GNA11,ZFAT,ZMYND10
    AU-rich element binding TIAL1,HNRNPA0,EXOSC7,ELAVL4,EXOSC9,CPSF5,EXOSC8,NUDT21,ELAVL1,APOBEC1
    poly(A) RNA binding NOLC1,PA2G4,TFB1M,MRPS31,ITM2B,IPO5,SNRPN,RBMX2,AGO3,YARS
    transcription factor activity, sequence-specific DNA binding FOXG1D,GABPB1,FOXG1C,NKX2-5,ZNF561,MEOX1,ZSCAN4F,POU5F2,ELF2,NEUROD2
    mRNA binding FYTTD1,CELF3,CROP,TPR,TSN,ADARB1,QKI,DCP1B,PARK7,RBPMS2B

    Interacting Protein

    ZFP36L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZFP36L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZFP36L1.

    MAPK14;TERF1;PAFAH1B2;SF1;mexB;yrrO;TFAP2C;ACD;TINF2;POT1;YWHAZ

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