WARS2
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Official Full Name
tryptophanyl tRNA synthetase 2, mitochondrial -
Overview
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. -
Synonyms
WARS2;tryptophanyl tRNA synthetase 2, mitochondrial;tryptophanyl-tRNA synthetase, mitochondrial;TrpRS;tryptophan tRNA ligase 2;mitochondrial;(Mt)TrpRS;Mitochondrial tryptophanyl tRNA synthetase 2;Tryptophanyl tRNA synthetase 2;tryptophan-tRNA ligase;tryptophan--tRNA ligase;tryptophan tRNA ligase 2, mitochondrial
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- His&T7
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| WARS2-1273H | Recombinant Human WARS2 protein, His & T7-tagged | E.coli | Human | His&T7 | Met1~Leu360 |
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| Wars2-1274M | Recombinant Mouse Wars2 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Met1~Leu360 |
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| WARS2-160H | Recombinant Human WARS2 Protein, His-tagged | E.coli | Human | His |
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| WARS2-18425M | Recombinant Mouse WARS2 Protein | Mammalian Cells | Mouse | His |
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| WARS2-2116Z | Recombinant Zebrafish WARS2 | Mammalian Cells | Zebrafish | His |
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| WARS2-369HCL | Recombinant Human WARS2 293 Cell Lysate | HEK293 | Human | Non |
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| WARS2-10105M | Recombinant Mouse WARS2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| WARS2-10105M-B | Recombinant Mouse WARS2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
WARS2 involved in several pathways and played different roles in them. We selected most pathways WARS2 participated on our site, such as Aminoacyl-tRNA biosynthesis,Gene Expression,Mitochondrial tRNA aminoacylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with WARS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| tRNA Aminoacylation | DARS,EARS2,FARS2,MADD,AIMP1,AIMP2,AARS,KARS,EEF1E1,FARSB |
| Mitochondrial tRNA aminoacylation | FARS2,EARS2,KARS |
| Gene Expression | NR2F6,COX16,ADARB1,ZNF556,TBX5A,CBX3A,KIAA1456,ZNF256,TAF1C,ZNF496 |
| Aminoacyl-tRNA biosynthesis | RARS,CARS,LARS2,FARS2,KARS,DARS,FARSB,HARS,SARS,PET112L |
Protein Function
WARS2 has several biochemical functions, for example, ATP binding,tryptophan-tRNA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WARS2 itself. We selected most functions WARS2 had, and list some proteins which have the same functions with WARS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tryptophan-tRNA ligase activity | WARS |
| ATP binding | NEK6,BRAF,NIM1,MYO18A,DHX37,TESK2,MYH8,CAD,NWD1,DHX16 |
Interacting Protein
WARS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WARS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of WARS2.
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