VIPR2
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Official Full Name
vasoactive intestinal peptide receptor 2 -
Overview
Vasoactive intestinal peptide (VIP; MIM 192320) and pituitary adenylate cyclase activating polypeptide (PACAP; MIM 102980) are homologous peptides that function as neurotransmitters and neuroendocrine hormones. While the receptors for VIP and PACAP share homology, they differ in their substrate specificities and expression patterns. See VIPR1 (MIM 192321) and ADCYAP1R1(MIM 102981). -
Synonyms
VIPR2;vasoactive intestinal peptide receptor 2;VPAC2;VPCAP2R;FLJ16511;vasoactive intestinal polypeptide receptor 2;VIP-R-2;PACAP-R3;PACAP-R-3;OTTHUMP00000200015;OTTHUMP00000200016;OTTHUMP00000200017;PACAP type III receptor;helodermin-preferring VIP receptor;pituitary adenylate cyclase-activating polypeptide type III receptor
Recombinant Proteins
- Mouse
- Chicken
- Human
- Rat
- Zebrafish
- Mus musculus
- Mammalian Cell
- Human Cell
- E.coli expression system
- HEK293
- Mammalian cells
- HEK293T
- His
- Fc
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
VIPR2 involved in several pathways and played different roles in them. We selected most pathways VIPR2 participated on our site, such as cAMP signaling pathway,Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with VIPR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | HTR1B,LHB,CHRNA4B,LPAR6,GRM2A,MCHR1,TACR3,TAAR7F,GRIA2A,GABRE |
| cAMP signaling pathway | PDE4C,SLC9A1,PIK3R1,F2R,GRIA1,ATP1A1,PTCH1,GHRL,CALM1,NPY1R |
Protein Function
VIPR2 has several biochemical functions, for example, G-protein coupled receptor activity,vasoactive intestinal polypeptide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VIPR2 itself. We selected most functions VIPR2 had, and list some proteins which have the same functions with VIPR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | F2RL1,GRM2A,OLFR688,OLFR50,GPR61,TAS2R108,TRHRB,OLFCS2,TAS2R106,EXORH |
| vasoactive intestinal polypeptide receptor activity | VIPR1B,ADCYAP1R1,GHRHRL,VIPR1,ADCYAP1R1A |
Interacting Protein
VIPR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VIPR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of VIPR2.
Hacd3;URM1
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References
- Shibata, M; Hisajima, T; et al. Morphological relationships between peptidergic nerve fibers and immunoglobulin A-producing lymphocytes in the mouse intestine. BRAIN BEHAVIOR AND IMMUNITY 22:158-166(2008).
- Cassiman, D; Sinelli, N; et al. Human hepatic progenitor cells express vasoactive intestinal peptide receptor type 2 and receive nerve endings. LIVER INTERNATIONAL 27:323-328(2007).
