VIL1
-
Official Full Name
villin 1 -
Overview
This gene encodes a member of a family of calcium-regulated actin-binding proteins.This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments.Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. -
Synonyms
VIL1;villin 1;VIL;villin-1;D2S1471
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- His
- GST
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
VIL1 involved in several pathways and played different roles in them. We selected most pathways VIL1 participated on our site, such as Regulation of Actin Cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with VIL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Actin Cytoskeleton | FGF1A,RHOAC,VAV2,PPP1CBL,FGF16,ITGB1,ACTN2B,PFN2L,FGD1,FGF19 |
Protein Function
VIL1 has several biochemical functions, for example, actin filament binding,calcium ion binding,cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Some of the functions are cooperated with other proteins, some of the functions could acted by VIL1 itself. We selected most functions VIL1 had, and list some proteins which have the same functions with VIL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type endopeptidase inhibitor activity involved in apoptotic process | DPEP1,PRDX5,BIRC5,RPS6KA3,PRDX3,TFAP2B,IGF1RA,SERPINB1A,BIRC2,BIRC3 |
| identical protein binding | SKP2,FHOD1,CDC42,EGFR,PPP1R13L,NELL2,PRDX1,L1CAM,ESR1,ADIPOR1 |
| protein homodimerization activity | TREX1,MAFA,SLC11A1,HSD17B4,SRF,LMLN,PVRL1,RELA,AGXT,PTPRE |
| actin filament binding | CORO1A,ESPN,CORO1C,MYO18A,SYNE1,ANTXR1,TLN1,MYO1E,SHROOM3,PLS1 |
| calcium ion binding | EMR2,MMP13,ANXA4,NUCB2A,PROCA,NOX5,TPO,VSNL1A,C1S,NOTCH2NL |
| protein binding | MAGEA9,WLS,ERBB2,XRCC4,ZHX3,KRT86,ARNTL1B,ZNF410,XBP1,SLC9A3R1 |
| phosphatidylinositol-4,5-bisphosphate binding | KCNJ1,RS1,FCHO2,KLHL8,CCDC167,FAM123A,LDLRAP1,RAB35,COMMD1,CHMP3 |
| lysophosphatidic acid binding | LPAR1,GAP43 |
Interacting Protein
VIL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VIL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VIL1.
PLCG1;PPM1B;TEX11
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