VENTX

  • Official Full Name

    VENT homeobox
  • Overview

    This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas.
  • Synonyms

    VENTX;VENT homeobox;VENT homeobox homolog (Xenopus laevis) , VENT like homeobox 2 , VENTX2;homeobox protein VENTX;HPX42B;MGC119910;MGC119911;hemopoietic progenitor homeobox protein VENTX2;NA88A;VENT homeobox homolog;VENT like homeobox 2;VENT like homeobox protein 2;VENT-like homeobox protein 2;VENTX_HUMAN;VENTX2;VENT-like homeobox 2
Cat.# Product name Source (Host) Species Tag Protein Length Price
VENTX-415HCL Recombinant Human VENTX 293 Cell Lysate HEK293 Human Non
VENTX-2121H Recombinant Human VENTX Protein (1-258 aa), GST-tagged E.coli Human GST 1-258 aa
VENTX-5081H Recombinant Human VENTX Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK

    Involved Pathway

    VENTX involved in several pathways and played different roles in them. We selected most pathways VENTX participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VENTX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    VENTX has several biochemical functions, for example, protein binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VENTX itself. We selected most functions VENTX had, and list some proteins which have the same functions with VENTX. You can find most of the proteins on our site.

    Function Related Protein
    protein binding EIF3G,CHUK,STUB1,NFKBID,VCP,CBX5,PRMT3,NPLOC4,IFITM1,ERCC8
    sequence-specific DNA binding HOXB9,DMBX1B,PBX4,PPARD,NR2F2,PBX2,FOXO1,DBX2,FOXC1B,NFIL3-5

    Interacting Protein

    VENTX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VENTX here. Most of them are supplied by our site. Hope this information will be useful for your research of VENTX.

    DAB1;KRTAP12-2;KRTAP12-4;C1orf94;RBPMS;TBX15;TBX22

    Resources

    References

    • Zhao, J; Lambert, G; et al. The transcription factor Vox represses endoderm development by interacting with Casanova and Pou2. DEVELOPMENT 140:1090-1099(2013).
    • Schuff, M; Siegel, D; et al. Characterization of Danio rerio Nanog and Functional Comparison to Xenopus Vents. STEM CELLS AND DEVELOPMENT 21:1225-1238(2012).

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