UQCR10
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Official Full Name
ubiquinol-cytochrome c reductase, complex III subunit X -
Overview
UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane. -
Synonyms
QCR9;UCRC;HSPC051;HSPC119;HSPC151;UCCR7.2;cytochrome b-c1 complex subunit 9;OTTHUMP00000199673;OTTHUMP00000199674;complex III subunit 9;complex III subunit X;cytochrome C1, nonheme 7kDa protein;cytochrome c1 non-heme 7 kDa protein;ubiquinol-cytochrome c reductase complex (7.2 kD);ubiquinol-cytochrome c reductase complex 7.2 kDa protein;ubiquinol-cytochrome c reductase, complex III subunit X, 7.2kDa;UQCR10;ubiquinol-cytochrome c reductase, complex III subunit X
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UQCR10-5629C | Recombinant Chicken UQCR10 | Mammalian Cell | Chicken | His |
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| UQCR10-490HCL | Recombinant Human UQCR10 293 Cell Lysate | HEK293 | Human | Non |
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| UQCR10-2152H | Recombinant Human UQCR10 Protein (1-63 aa), GST-tagged | E.coli | Human | GST | 1-63 aa |
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Involved Pathway
UQCR10 involved in several pathways and played different roles in them. We selected most pathways UQCR10 participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with UQCR10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Huntingtons disease | TFAM,PPIF,RCOR1,NDUFC2-KCTD14,BDNF,UCP1,ATP5G1,TBPL2,PLCB2,NDUFA9 |
| Oxidative phosphorylation | SDHB,NDUFS5,NDUFB3,ATP6V0A1,ATP6V1C1,ATP6V0C,NDUFA1,ATP6V0E2,ATP6V0E,MT-ND1 |
| Non-alcoholic fatty liver disease (NAFLD) | SDHA,PRKAA2,PIK3R5,FASLG,NDUFB1,COX8C,SOCS3,LEP,TNFRSF1A,NDUFS2 |
| Metabolic pathways | HADH,B4GALNT1,ATP5A1,HSD11B1,COASY,PDHA1,PYGB,mt-Atp8,PDXP,EXT1C |
| Alzheimers disease | SDHD,APOE,NDUFS5,NDUFA13,GRIN1,ADAM10,ATP5E,CAPN2,NDUFB4,NDUFAB1 |
| Parkinsons disease | NDUFA4L2,VDAC1,UBE2G2,ATP5F1,NDUFV1,APAF1,UQCR11,TH,SNCAIP,PINK1 |
| Cardiac muscle contraction | COX7C,ATP1A4,CACNG1,SLC8A1,UQCRC2A,ATP1A1,COX5AA,TPMA,CACNA1DA,CACNB4 |
Protein Function
UQCR10 has several biochemical functions, for example, ubiquinol-cytochrome-c reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UQCR10 itself. We selected most functions UQCR10 had, and list some proteins which have the same functions with UQCR10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquinol-cytochrome-c reductase activity | UQCRC1,UQCR11,UQCRFS1,UQCRQ,UQCRH |
Interacting Protein
UQCR10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UQCR10 here. Most of them are supplied by our site. Hope this information will be useful for your research of UQCR10.
UQCRC1;S100A4;KPNB1;CLPP;NDUFA9;NDUFA11;TIMMDC1
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References
- Berry, EA; De Bari, H; et al. Unanswered questions about the structure of cytochrome bc(1) complexes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1827:1258-1277(2013).
- Kriaucionis, S; Paterson, A; et al. Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome. MOLECULAR AND CELLULAR BIOLOGY 26:5033-5042(2006).
