UPP2
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Official Full Name
uridine phosphorylase 2 -
Synonyms
UPP2;uridine phosphorylase 2;UDRPASE2;UP2;UPASE2;Liver specific uridine phosphorylase;UPase 2;UPP 2;UPP2_HUMAN;UrdPase 2;uridine phosphorylase-2;liver-specific uridine phosphorylase
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ (in vitro)
- GST
- His
- His&T7
- Non
- Flag
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UPP2-3604H | Recombinant Human UPP2, GST-tagged | E.coli | Human | GST | 1-317aa | |
| UPP2-10493Z | Recombinant Zebrafish UPP2 | Mammalian Cell | Zebrafish | His |
|
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| Upp2-1295M | Recombinant Mouse Upp2 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Met1~Ser320 |
|
| UPP2-493HCL | Recombinant Human UPP2 293 Cell Lysate | HEK293 | Human | Non |
|
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| UPP2-15HFL | Recombinant Human UPP2 Protein, Full Length, C-Flag tagged | HEK293T | Human | Flag | Full L. Full Length |
|
| UPP2-20HFL | Recombinant Human UPP2 Protein, Full Length, N-GST tagged | Wheat Germ (in vitro) | Human | GST | Full L. Full Length |
|
| Upp2-6849M | Recombinant Mouse Upp2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
Involved Pathway
UPP2 involved in several pathways and played different roles in them. We selected most pathways UPP2 participated on our site, such as Drug metabolism - other enzymes,Fluoropyrimidine Activity,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UPP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pyrimidine salvage reactions | DCK |
| Pyrimidine catabolism | DPYS,DPYDA.1,DPYD,PROZA,TYMP |
| Metabolic pathways | CKMT2,Atp5k,NDUFV2,ACOT5,GAD2,PAPSS2B,HSD3B4,ACSL1A,ALDH7A1,POLE2 |
| Metabolism | Sult2a2,PPM1L,CYP2A13,ARF3,ACMSD,B3GNT2A,OAZ2B,SLC25A27,KCNS3A,STARD5 |
| Fluoropyrimidine Activity | SLC22A7,CES1,DPYD,DHFR,DPYS,TYMP |
| Metabolism of nucleotides | TYMP,DUT,PROZA,ADSS,DTYMK,DCK,DPYS,NUDT16,ADA,PAICS |
| Pyrimidine metabolism | UCKL1,udp,TRR1,POLD2,ITPA,POLR2GL,PNP,POLR3B,POLR3K,NME4 |
| Drug metabolism - other enzymes | CDA,IMPDH1,Ces2e,UGT2B15,Ces2c,HPRT1,UGT5G1,UGT2A3,UPP1,NAT |
Protein Function
UPP2 has several biochemical functions, for example, protein binding,uridine phosphorylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UPP2 itself. We selected most functions UPP2 had, and list some proteins which have the same functions with UPP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| uridine phosphorylase activity | UPP1 |
| protein binding | RAD21,MT1G,COX6B2,NDUFB10,SH3PXD2A,DPM1,IL1RL1,FMNL3,JAK2,ADORA2A |
Interacting Protein
UPP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UPP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UPP2.
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References
- Ma, GY; Zhang, JZ; et al. Toxoplasma gondii: Proteomic analysis of antigenicity of soluble tachyzoite antigen. EXPERIMENTAL PARASITOLOGY 122:41-46(2009).
- Tokunaga, Y; Sasaki, H; et al. Clinical role of orotate phosphoribosyl transferase and dihydropyrimidine dehydrogenase in colorectal cancer treated with postoperative fluoropyrimidine. SURGERY 141:346-353(2007).
- Liu, MP; Cao, DL; et al. Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors. CANCER RESEARCH 58:5418-5424(1998).
