UCP2
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Official Full Name
uncoupling protein 2 (mitochondrial, proton carrier)
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Overview
UCP2 also known as mitochondrial uncoupling protein 2 is a 33 kD member of the mitochondrial anion carrier protein family. This protein is expressed in the mitochondria and is highly expressed in brain, kidney, liver, brown adipose tissue, heart, and musc -
Synonyms
UCP2; uncoupling protein 2 (mitochondrial, proton carrier); mitochondrial uncoupling protein 2; SLC25A8; UCP 2; solute carrier family 25 member 8; UCPH; BMIQ4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Canis lupus familiaris (Dog) (Canis familiaris)
- Cyprinus carpio (Common carp)
- Danio rerio (Zebrafish) (Brachydanio rerio)
- Homo sapiens (Human)
- Human
- Mouse
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Sus scrofa (Pig)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- Fc
- Avi
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
UCP2 involved in several pathways and played different roles in them. We selected most pathways UCP2 participated on our site, such as Electron Transport Chain, Energy Metabolism, FOXA2 and FOXA3 transcription factor networks, which may be useful for your reference. Also, other proteins which involved in the same pathway with UCP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Electron Transport Chain | COX17;COX11;COX8A;COX6A1;SLC25A27;SLC25A14;COX15;ATP5L;COX5B |
| Energy Metabolism | ESRRA;UCP2;GABPA;TFB1M;MEF2B;UCP3;MYBBP1A;PPARGC1B;TFB2M |
| FOXA2 and FOXA3 transcription factor networks | KCNJ11;CPT1B;CEBPA;UCP2;TTR;CPT1C;DLK1;FOXF1;CPT1A |
| Metabolism | ADA;NOSTRIN;AZIN2;CYP2K18;CYP2Y3;MARCKSA;ELOVL1A;PMVK;BCKDK |
| Mitochondrial Uncoupling Proteins | SLC25A27;SLC25A14;UCP2;UCP3 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | SCO1;NDUFAF3;C20orf7;TIMMDC1;UCP3;FAM36A;ETFA;UCP2;ETFB |
| The citric acid (TCA) cycle and respiratory electron transport | NDUFAF3;ADHFE1;COX14;ETFA;NDUFAF2;COX18;PDK2;NDUFAF5;PDPR |
| The fatty acid cycling model | SLC25A14;UCP2;UCP3;SLC25A27 |
UCP2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UCP2 itself. We selected most functions UCP2 had, and list some proteins which have the same functions with UCP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BFAR;ZNF276;TRPM8;SMARCC1;UBE2V2;TLX2;UQCC1;GPATCH4;SMCP |
UCP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UCP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UCP2.
KRTAP10-7; pepP
Research Area
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