UBE2J1

  • Official Full Name

    ubiquitin-conjugating enzyme E2, J1

  • Overview

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]

  • Synonyms

    UBE2J1;ubiquitin-conjugating enzyme E2, J1;UBC6;Ubc6p;CGI-76;NCUBE1;HSPC153;HSPC205;NCUBE-1;HSU93243;ubiquitin-conjugating enzyme E2 J1;HSUBC6e;ubiquitin-conjugating enzyme E2, J1, U;non-canonical ubiquitin-conjugating enzyme 1;yeast ubiquitin-conjugating enzyme UBC6 homolog E;ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Mouse
  • Sf9 Insect Cell
  • Mammalian Cell
  • HEK293
  • E.coli
  • HEK293T
  • GST
  • His
  • Non
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
UBE2J1-126H Recombinant Human UBE2J1, GST-tagged Sf9 Insect Cell Human GST
UBE2J1-12784Z Recombinant Zebrafish UBE2J1 Mammalian Cell Zebrafish His
UBE2J1-6327C Recombinant Chicken UBE2J1 Mammalian Cell Chicken His
UBE2J1-572HCL Recombinant Human UBE2J1 293 Cell Lysate HEK293 Human Non
UBE2J1-312H Recombinant Human UBE2J1 Protein, His-tagged E.coli Human His
UBE2J1-4945H Recombinant Human UBE2J1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Ube2j1-6790M Recombinant Mouse Ube2j1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    UBE2J1 involved in several pathways and played different roles in them. We selected most pathways UBE2J1 participated on our site, such as Ubiquitin mediated proteolysis,Protein processing in endoplasmic reticulum,Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2J1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis UBE2Z,BTRC,RNF7,ANAPC1,CDC26,UBE2IA,UBE2KB,UBE3B,MGRN1A,UBE4A
    Parkinsons disease MT-ND1,GPR37,NDUFC1,PRKACA,CYCS,NDUFA1,VDAC3,UBA1,TH,SLC25A31
    Protein processing in endoplasmic reticulum CUL1B,HSPA1A,DNAJB1A,NFE2L2,CRYABA,BCL2,DNAJC3A,ERP29,ATF4B1,ATF4

    Protein Function

    UBE2J1 has several biochemical functions, for example, ATP binding,ubiquitin conjugating enzyme activity,ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2J1 itself. We selected most functions UBE2J1 had, and list some proteins which have the same functions with UBE2J1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding LARS,STK39,MYH6,MAPK8B,CHD6,MYO1F,CSNK1E,SMYHC2,SRR,ATP1A1B
    ubiquitin protein ligase activity CBLL1,RNF220,RNF2,TRAIP,FANCL,TRIM37,FBXW11,UBE2R2,UBE2G1,AMFR
    ubiquitin conjugating enzyme activity UBE2Z,UBE2G1,UBE2T,UBE2B,UBE2D2A,UBE2H,UBE2S,UBE2R2,UBE2V2,UBE2E3
    ubiquitin protein ligase binding NFKBIA,YWHAE,PRKAR2A,CD40,AMBRA1,RBX1,ERLIN2,USP13,PPARGC1A,TANK

    Interacting Protein

    UBE2J1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2J1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2J1.

    Map3k1;PJA2;CREB3;TRIM27;UBA1;BRCA1;BIRC2;q6nr77_human;LRSAM1;SYVN1;RNF2;TOPORS;RNF5

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