TYW3
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Official Full Name
tRNA-yW synthesizing protein 3 homolog -
Overview
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006). -
Synonyms
TYW3;tRNA-yW synthesizing protein 3 homolog (S. cerevisiae);C1orf171, chromosome 1 open reading frame 171;tRNA wybutosine-synthesizing protein 3 homolog;FLJ40918;tRNA-yW-synthesizing protein 3;C1orf171
Recombinant Proteins
- Chicken
- Rhesus macaque
- Zebrafish
- Human
- Mouse
- Mammalian Cells
- HEK293
- His
- Non
- DDK
- Myc
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TYW3-5014C | Recombinant Chicken TYW3 | Mammalian Cells | Chicken | His |
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| TYW3-5045R | Recombinant Rhesus monkey TYW3 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| TYW3-725Z | Recombinant Zebrafish TYW3 | Mammalian Cells | Zebrafish | His |
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| TYW3-611HCL | Recombinant Human TYW3 293 Cell Lysate | HEK293 | Human | Non |
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| TYW3-1881H | Recombinant Human TYW3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| TYW3-4858R | Recombinant Rhesus Macaque TYW3 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| TYW3-4858R-B | Recombinant Rhesus Macaque TYW3 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| Tyw3-6761M | Recombinant Mouse Tyw3 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
TYW3 involved in several pathways and played different roles in them. We selected most pathways TYW3 participated on our site, such as 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis,Gene Expression,Synthesis of wybutosine at G37 of tRNA(Phe), which may be useful for your reference. Also, other proteins which involved in the same pathway with TYW3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Synthesis of wybutosine at G37 of tRNA(Phe) | TYW1,LCMT2,TRMT5,TRMT12,TYW5 |
| tRNA processing | CDKAL1,WDR4,TYW5,POP1,CCDC76,C2orf49,ZBTB8OS,OSGEP,ELAC2,TRDMT1 |
| tRNA modification in the nucleus and cytosol | KIAA1456,TRMT11,TRMT61A,QTRT1,PUS7,LCMT2,LBH,TPRKB,QTRTD1,THG1L |
| wybutosine biosynthesis | TYW1,LCMT2 |
| 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis | TYW1 |
| Gene Expression | NR2F1,D1BWG0212E,SAP18,ZNF202,COX18,SPCS3,HELZ2,ZNF37A,ZNF701,GTF3A |
Protein Function
TYW3 has several biochemical functions, for example, methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TYW3 itself. We selected most functions TYW3 had, and list some proteins which have the same functions with TYW3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| methyltransferase activity | SMYD2B,SUV39H1B,C2orf56,PRDM12,METTL8,PRDM13,NSUN6,PCMT,Mettl11b,FBLL1 |
Interacting Protein
TYW3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TYW3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TYW3.
ZWINT;Smchd1;Mis12
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