TUSC1
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Official Full Name
tumor suppressor candidate 1 -
Overview
This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis. -
Synonyms
TUSC1;tumor suppressor candidate 1;tumor suppressor candidate gene 1 protein;TSG 9;MGC131751;TSG9;TSG-9
Recombinant Proteins
- Mouse
- Human
- Rhesus macaque
- Mammalian Cells
- E.coli
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TUSC1-17637M | Recombinant Mouse TUSC1 Protein | Mammalian Cells | Mouse | His |
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| TUSC1-31634TH | Recombinant Human TUSC1, His-tagged | E.coli | Human | His | 59-212 a.a. |
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| TUSC1-5030R | Recombinant Rhesus monkey TUSC1 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| TUSC1-4843R | Recombinant Rhesus Macaque TUSC1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| TUSC1-4843R-B | Recombinant Rhesus Macaque TUSC1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| TUSC1-9773M | Recombinant Mouse TUSC1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TUSC1-9773M-B | Recombinant Mouse TUSC1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TUSC1 involved in several pathways and played different roles in them. We selected most pathways TUSC1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TUSC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TUSC1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TUSC1 itself. We selected most functions TUSC1 had, and list some proteins which have the same functions with TUSC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
TUSC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUSC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TUSC1.
Resources
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References
- Meistermann, H; Gao, JJ; et al. A Novel Immuno-Competitive Capture Mass Spectrometry Strategy for Protein-Protein Interaction Profiling Reveals That LATS Kinases Regulate HCV Replication Through NS5A Phosphorylation. MOLECULAR & CELLULAR PROTEOMICS 13:3040-3048(2014).
- Thompson, JW; Nagel, J; et al. Quantitative Lys-epsilon-Gly-Gly (diGly) Proteomics Coupled with Inducible RNAi Reveals Ubiquitin-mediated Proteolysis of DNA Damage-inducible Transcript 4 (DDIT4) by the E3 Ligase HUWE1. JOURNAL OF BIOLOGICAL CHEMISTRY 289:28942-28955(2014).
