TUBB
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Official Full Name
tubulin, beta class I -
Overview
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. -
Synonyms
TUBB;tubulin, beta class I;M40;TUBB1;TUBB5;OK/SW-cl.56;tubulin beta chain;beta1-tubulin;beta 5-tubulin;beta-4 tubulin;beta Ib tubulin;class I beta-tubulin;tubulin beta-1 chain;tubulin beta-5 chain;tubulin beta polypeptide;tubulin, beta polypeptide
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- His
- GST
- T7
- Non
- Flag
- DDK
- Myc
- Avi
- Fc
Involved Pathway
TUBB involved in several pathways and played different roles in them. We selected most pathways TUBB participated on our site, such as Phagosome,Gap junction,Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gap junction | PRKG1,RAF1B,GNA15.1,TUBA4L,PRKACBA,GNAI2A,ADCY2B,GRB2,CSNK1DB,ADRB3B |
| Phagosome | TAP1,VAMP3,RAB5C,ATP6V1C2,SFTPD,HLA-DQB1,H2-AA,ACTG1,BLB2,FCGR3 |
| Pathogenic Escherichia coli infection | ABL1,TUBAL3,TUBA3D,HCLS1,NCK1,TUBB2A,ARPC5L,ITGB1,YWHAZ,RHOA |
Protein Function
TUBB has several biochemical functions, for example, GTP binding,GTPase activating protein binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBB itself. We selected most functions TUBB had, and list some proteins which have the same functions with TUBB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex binding | RARB,SHANK1,CDK5RAP2,MTHFR,KCTD5,RAN,CFLAR,YWHAB,FBN1,AKAP5 |
| protein binding | REXO1L1,TMEM30B,MYO9B,SKAP1,RALB,NIPAL3,BAK1,SEPT1,OLA1,EPHA2 |
| GTP binding | RAB38,TUBA1L,SEPT5A,RAB9A,RAC3,IRGE4,RRAGC,HHAT,EIF5B,RHEB |
| GTPase activity | RAB25A,RAB17,RAB35B,RAB21,EEF2B,RAB1BB,GNA15.4,RRAGA,RAB5AA,TUBA7L |
| structural molecule activity | LELP1,KRT84,LAMC3,LCE1F,CLDND,KRT13,SNTG2,KRT6A,KRT79,NGS |
| structural constituent of cytoskeleton | ARPC2,EPB42,ADD3,ACTL7A,TUBA8L4,TUBB4B,F-KER,TUBGCP4,CCDC6,TUBG1 |
| ubiquitin protein ligase binding | TMEM173,ARRB2,CUL4B,TRIB1,RBX1,PCBP2,FZD6,HSPA8,ANAPC2,ARIH1 |
| GTPase activating protein binding | GNAI3,FMNL1,GNAO1,TSC1,GAPVD1,PIN1,PLCD1,PTBP3,CDH1,MEX3B |
| MHC class I protein binding | LILRB2,PILRB,ATP5A1,PILRB2,CD8A,CD244,HLA-E,VCP,TAP1,BCAP31 |
Interacting Protein
TUBB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBB here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBB.
LRRK2;SNW1;P;TINF2;EBNA-LP;PPP2R2B;ADRBK1;STAU1;NFKB2;NFKBIE
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