TSPAN6

  • Official Full Name

    tetraspanin 6
  • Overview

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene.
  • Synonyms

    TSPAN6;tetraspanin 6;TM4SF6, transmembrane 4 superfamily member 6;tetraspanin-6;T245;TSPAN 6;6720473L21Rik;A15 homolog;AI316786;DKFZp469J2433;MGC117923;MGC133784;Putative NF kappa B activating protein 321;T245 protein;Tetraspan TM4SF;Tetraspanin TM4 D;Tetraspanin TM4D;Tm4sf;TM4SF6;Transmembrane 4 superfamily member 6;Tspan6 protein;tetraspanin TM4-D;putative NF-kappa-B-activating protein 321;TSPAN-6

Recombinant Proteins

  • Chicken
  • Human
  • Bovine
  • Pongo Abelii
  • Mus musculus
  • Mouse
  • Mammalian Cells
  • HEK293
  • E.coli
  • His
  • Non
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
TSPAN6-4982C Recombinant Chicken TSPAN6 Mammalian Cells Chicken His
TSPAN6-705HCL Recombinant Human TSPAN6 293 Cell Lysate HEK293 Human Non
RFL21961BF Recombinant Full Length Bovine Tetraspanin-6(Tspan6) Protein, His-Tagged E.coli Bovine His Full L. Full Length (1-245)
RFL28543HF Recombinant Full Length Human Tetraspanin-6(Tspan6) Protein, His-Tagged E.coli Human His Full L. Full Length (1-245)
RFL29414PF Recombinant Full Length Pongo Abelii Tetraspanin-6(Tspan6) Protein, His-Tagged E.coli Pongo Abelii His Full L. Full Length (1-245)
RFL29900MF Recombinant Full Length Mouse Tetraspanin-6(Tspan6) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length (1-245)
Tspan6-6693M Recombinant Mouse Tspan6 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK

    Involved Pathway

    TSPAN6 involved in several pathways and played different roles in them. We selected most pathways TSPAN6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSPAN6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    TSPAN6 has several biochemical functions, for example, protein binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TSPAN6 itself. We selected most functions TSPAN6 had, and list some proteins which have the same functions with TSPAN6. You can find most of the proteins on our site.

    Function Related Protein
    protein binding RBM25,ROBO1,FSTL5,GNB1B,GSK3A,AGR3,TRIM2,TMEM183A,WLS,Trl
    signal transducer activity CELSR3,TAAR7D,LITAF,OLFR495,NEK6,TAAR13C,DRD2A,TAS2R104,GNGT2A,TAAR14J

    Interacting Protein

    TSPAN6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSPAN6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSPAN6.

    CHD3;RIF1;NSG2

    Resources

    Research Area

    Regulator of NFkB

    References

    • Gopal, AK; Tarantolo, SR; et al. Phase 1b study of otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR (TM) therapeutic protein, in combination with rituximab and bendamustine in relapsed indolent lymphoma patients. INVESTIGATIONAL NEW DRUGS 32:1213-1225(2014).
    • Dakshinamoorthy, G; von Gegerfelt, A; et al. Evaluation of a Multivalent Vaccine against Lymphatic Filariasis in Rhesus macaque Model. PLOS ONE 9:-(2014).

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