TSC22D1

  • Official Full Name

    TSC22 domain family, member 1

  • Overview

    This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

  • Synonyms

    TSC22D1;TSC22 domain family, member 1;TGFB1I4, transforming growth factor beta 1 induced transcript 4;TSC22 domain family protein 1;MGC17597;TSC22;Cerebral protein 2;DKFZp686O19206;Hucep 2;Hucep2;KIAA1994;OTTHUMP00000040978;Regulatory protein TSC 22;Regulatory protein TSC22;RP11 269C23.2;TGFB stimulated clone 22 homolog;TGFB1I4;Transforming growth factor beta 1 induced transcript 4;Transforming growth factor beta 1 induced transcript 4 protein;Transforming growth factor beta stimulated protein TSC 22;TSC 22;TSC22 domain family 1 isoform 2;TSC22 domain family member 1;regulatory protein TSC-22;TGFbeta-stimulated clone 22;TGFB-stimulated clone 22 homolog;transcriptional regulator TSC-22;transforming growth factor beta-stimulated protein TSC-22;transforming growth factor beta-1-induced transcript 4 protein;Ptg-2

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Non
Cat.# Product name Source (Host) Species Tag Protein Length Price
TSC22D1-3442H Recombinant Human TSC22D1, GST-tagged E.coli Human GST 2-144aa
TSC22D1-12015Z Recombinant Zebrafish TSC22D1 Mammalian Cells Zebrafish His
TSC22D1-1996C Recombinant Chicken TSC22D1 Mammalian Cells Chicken His
TSC22D1-30748TH Recombinant Human TSC22D1, His-tagged E.coli Human His 40-144 a.a.
TSC22D1-6668C Recombinant Chicken TSC22D1 Mammalian Cells Chicken His
TSC22D1-877H Recombinant Human TSC22D1 protein, His-tagged E.coli Human His Met1-Ala144
Tsc22d1-999M Recombinant Mouse Tsc22d1 protein, His-tagged E.coli Mouse His Met1-Ala143
TSC22D1-724HCL Recombinant Human TSC22D1 293 Cell Lysate HEK293 Human Non

    Involved Pathway

    TSC22D1 involved in several pathways and played different roles in them. We selected most pathways TSC22D1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSC22D1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    TSC22D1 has several biochemical functions, for example, protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TSC22D1 itself. We selected most functions TSC22D1 had, and list some proteins which have the same functions with TSC22D1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TELO2,MB21D2,MTM1,VSTM2L,PIK3CA,LRRC6,UBE2L6,PARP1,TPRGL,PSMD2
    transcription factor activity, sequence-specific DNA binding TTC4,TCF7L2,FOXL1,TBP,DBPB,DBPA,HOXB3A,ZFP42,DMRT2B,NEUROG1

    Interacting Protein

    TSC22D1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSC22D1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSC22D1.

    TPT1;WDYHV1;APLP1;SETDB1;CCDC90B;a2j422_human;4504555

    Resources

    Research Area

    Cancer Stem Cell Transcription Factors
    Hematopoietic Stem Cell Transcription Factors and Regulators

    References

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