TRPV2
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Official Full Name
transient receptor potential cation channel, subfamily V, member 2 -
Overview
ion channel that may be activated by high temperature; may transduce high threshold heat responses in sensory ganglia -
Synonyms
TRPV2;transient receptor potential cation channel, subfamily V, member 2;transient receptor potential cation channel subfamily V member 2;VRL;VRL 1;VRL1;OTRPC2;osm-9-like TRP channel 2;vanilloid receptor-like protein 1;VRL-1;MGC12549
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- His&Flag
- His&Fc&Avi
Involved Pathway
TRPV2 involved in several pathways and played different roles in them. We selected most pathways TRPV2 participated on our site, such as Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPV2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inflammatory mediator regulation of TRP channels | BDKRB1,CALM2,PRKACB,PIK3CB,CALML5,TRPV4,BDKRB2,PIK3CA,PTGER2,CYP4A10 |
Protein Function
TRPV2 has several biochemical functions, for example, calcium channel activity,cation channel activity,ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPV2 itself. We selected most functions TRPV2 had, and list some proteins which have the same functions with TRPV2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ion channel activity | TRPC5A,TRPC4B,CHRNA1,TRPC2B,KCNA6A,CLCNKB,TRPC7B,TRPN1,KCNF1A,GRIK3 |
| cation channel activity | GRIN3B,ASIC3,GRIN2C,GAR1,TRPM1B,TRPV4,ASIC4A,ASIC1A,FAM38B,FAM26E |
| calcium channel activity | ITPR3,SLC24A1,ITPR1,RYR1,TMEM37,UBXN6,CACNA1DA,CACFD1,RYR2,GRIN3A |
| ion transmembrane transporter activity | S100A6,SFXN1,SFXN5B,PLP2,GJA1,SFXN5A,SFXN2,SFXN3,LASP1,SFXN4 |
Interacting Protein
TRPV2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPV2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPV2.
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References
- Entin-Meer, M; Levy, R; et al. The Transient Receptor Potential Vanilloid 2 Cation Channel Is Abundant in Macrophages Accumulating at the Peri-Infarct Zone and May Enhance Their Migration Capacity towards Injured Cardiomyocytes following Myocardial Infarction. PLOS ONE 9:-(2014).
