TRPC1
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Official Full Name
transient receptor potential cation channel, subfamily C, member 1 -
Overview
Transient receptor potential channel 1 (TRPC1) is a protein that in humans is encoded by the TRPC1 gene. -
Synonyms
trpc1;transient receptor potential cation channel, subfamily C, member 1;HTRP 1;HTRP1;MGC133334;MGC133335;Mtrp1;Short transient receptor potential channel 1;Transient receptor potential cation channel subfamily C member 1;Transient receptor potential channel 1;Transient receptor protein 1;TRP 1;TRP 1 protein;Trp related protein 1;TRP-1;TRP1;TRP1 protein;Trpc1 transient receptor potential cation channel subfamily C member 1;TRPC1_HUMAN;Trrp1;transient receptor potential protein;xtrpc1
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Rat
- Zebrafish
- Bovine
- Oryctolagus cuniculus (Rabbit)
- Mus musculus
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- His&Flag
- His&Fc&Avi
Involved Pathway
TRPC1 involved in several pathways and played different roles in them. We selected most pathways TRPC1 participated on our site, such as Glutamatergic synapse,Serotonergic synapse,Pancreatic secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Serotonergic synapse | CYP2D9,CYP2C55,GNG7,HTR2C,GNAI1,GNG11,PLCB2,PLA2G4A,CYP2J5,CYP2D26 |
Pancreatic secretion | CPA1,TPCN2,ATP1A3,CELA2B,Car2,RAB8A,CPB1,FXYD2,ITPR1,PLCB4 |
Glutamatergic synapse | SLC17A6,GNB4,SLC1A2,PLCB4,GNG8,GRIN2D,SLC1A1,GRM1,GLS2,GRIN3B |
Protein Function
TRPC1 has several biochemical functions, for example, calcium channel activity,cation channel activity,inositol 1,4,5 trisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPC1 itself. We selected most functions TRPC1 had, and list some proteins which have the same functions with TRPC1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
inositol 1,4,5 trisphosphate binding | TRPC2,TRPC2B,RPH3A,TRPC7,TRPC6A,TRPC4,TRPC6,CYTH2,TRPC3,TRPC7A |
ion channel binding | PACS2,PKP2,PDE4D,FAM115A,KCNAB1,PHPT1,FYN,DIAPH1,CTNNB1,S100A10 |
cation channel activity | CALHM2,TRPM1B,FAM38A,TRPV4,P2RX1,FAM38B,PKD2L1,ASIC1A,ASIC1C,CALHM3 |
protein binding | USP19,UVRAG,MCC,CRHR2,ERCC6L,GATA4,CEP55,RUVBL2,PHYHIPL,STX11 |
calcium channel activity | P2RX1,GRIN2A,GRIN2B,SLC24A5,GPM6A,TRPC4B,CACNA1SB,TRPM6,TPCN1,TRPC4A |
store-operated calcium channel activity | ZP3,TRPC7A,TRPC5,TRPC4,TRPC5A,ORAI3,TRPC2,ORAI2,TRPC6A,ORAI1 |
Interacting Protein
TRPC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPC1.
PKD2;MX1;q81xd6_bacan;o68752_yerpe;cya;yegQ;purL;carB;q5nel7_fratt;q5ni33_fratt;metE;q7cgs8_yerpe;pepP;ygfz_yerpe;proS;q7ch26_yerpe;q7chb5_yerpe;icmF1
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References
- Tran, VT; Ho, PT; et al. Mechanotransduction Channels of the Trabecular Meshwork. CURRENT EYE RESEARCH 39:291-303(2014).
- Liu, YW; Schneider, MF; et al. FGF2 activates TRPC and Ca2+ signaling leading to satellite cell activation. FRONTIERS IN PHYSIOLOGY 5:-(2014).