TRIM29

  • Official Full Name

    tripartite motif containing 29

  • Overview

    The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.

  • Synonyms

    TRIM29;tripartite motif containing 29;tripartite motif-containing protein 29;ataxia telangiectasia group D associated protein;ATDC;FLJ36085;tripartite motif protein TRIM29;tripartite motif-containing 29;ataxia telangiectasia group D-associated pro

Recombinant Proteins

  • Mouse
  • Rhesus macaque
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • Myc&DDK
  • Flag
  • His&Fc&Avi

    Involved Pathway

    TRIM29 involved in several pathways and played different roles in them. We selected most pathways TRIM29 participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM29 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine Signaling in Immune system MX2,HBEGF,TNFSF13B,PELI3,PEBP1,EDAR,SPNA2,IFIT3,NRG3,FCGR1B
    Interferon Signaling TRIM6,IFI27,IFITM2,IFIT10,TRIM8,FCGR1B,IFIT11,IRF9,TRIM68,USP18
    Immune System POLR3GLA,ASB18,LGALS3,PLD4,IFIT12,TLR10,KIF18A,PJA2,DTX3L,ASB14
    Interferon gamma signaling TRIM31,TRIM14,TRIM45,TRIM22,TRIM26,TRIM46,TRIM17,TRIM10,FCGR1B,GBP5

    Protein Function

    TRIM29 has several biochemical functions, for example, p53 binding,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM29 itself. We selected most functions TRIM29 had, and list some proteins which have the same functions with TRIM29. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding TAF3,TRIM9,NR5A1B,TRIM35,RNF133,ZNF34,TRIM43B,MUL1B,SEC23A,NEIL2
    protein binding HOXB6,CUL9,TDP1,DNAJB6,MTERFD2,GNB3,KCTD14,DLAT,SSNA1,C18orf56
    transcription factor activity, sequence-specific DNA binding MSC,TFAP2C,KLF1,ZNF501,ZNF286A,EHF,HER5,ATF4,TGIF2,SALL4
    p53 binding SETD8,CDKN2AIP,SIRT1,HSPD1,NUAK1,HTT,RNF20,PTTG1IP,TP53,GSK3B

    Interacting Protein

    TRIM29 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM29 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM29.

    GOLGA2;CEP70;LZTS2;MAD1L1;DVL2

    Resources

    References

    • Kanno, Y; Watanabe, M; et al. TRIM29 as a novel prostate basal cell marker for diagnosis of prostate cancer. ACTA HISTOCHEMICA 116:708-712(2014).
    • Huang, WB; Williamson, SR; et al. Novel markers of squamous differentiation in the urinary bladder. HUMAN PATHOLOGY 44:1989-1997(2013).

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