TRIM26
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Official Full Name
tripartite motif containing 26 -
Overview
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. -
Synonyms
TRIM26;tripartite motif containing 26;tripartite motif containing 26 , ZNF173;tripartite motif-containing protein 26;RNF95;ZNF173;Acid finger protein;AFP;CAM25547;RING finger protein 95;widely expressed acid zinc finger protein;Zinc finger protein 173;tripartite motif-containing 26
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
TRIM26 involved in several pathways and played different roles in them. We selected most pathways TRIM26 participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM26 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | POLR3H,ABI2,GZMM,BTR22,LILRB5,SPSB1,DEFA1,FCN2,GBP1,S100A12 |
| Interferon gamma signaling | GBP2,TRIM68,TRIM2,GBP1,TRIM45,TRIM31,IRF6,TRIM3,TRIM6,FCGR1B |
| Interferon Signaling | TRIM5,MX2,TRIM3,GBP1,GBP5,ARIH1,ADAR,IRF2,IFITM3,IFIT3 |
| Cytokine Signaling in Immune system | KPNA4,IFIT8,NUPL2,DUSP6,MX2,EIF4A2,SPTBN2,SPRED3,XAF1,IFI35 |
Protein Function
TRIM26 has several biochemical functions, for example, DNA binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM26 itself. We selected most functions TRIM26 had, and list some proteins which have the same functions with TRIM26. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ATP1B1,MAGEB2,MARK3,EMG1,IL4R,RBBP8,CERK,UPP2,GSTM4,RCOR1 |
| metal ion binding | ZDHHC16B,PRKCD,PRUNE2,SNRNP48,RASA3,CUBN,GNA15,ZNF219,KAT6A,ZBTB1 |
| zinc ion binding | PHF17,BRCA1,TAF3,PDLIM1,USP22,DRL,RORAB,PPARAA,NR2F5,ADH1A |
| DNA binding | ZNF333,FOXA2,HIST1H1T,DEDD2,ZNF443,ZBTB20,SOX6,KIF4A,RARAA,SETDB1B |
Interacting Protein
TRIM26 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM26 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM26.
AES;THAP1;MAGEA6;UBE2D1;MNAT1;UBE2D3;UBE2D2;RABEP1;q5ngv3_fratt;purB;metE;fliD;yhdL;asnO2;rsmH
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References
- Zhao, N; Wang, XL; et al. Tripartite Motif-Containing 22 Gene-364T/C Polymorphism Associated With Hepatitis B Virus Infection in Chinese Han Population. HEPATITIS MONTHLY 14:-(2014).
- Zoumpoulidou, G; Broceno, C; et al. Role of the Tripartite Motif Protein 27 in Cancer Development. JOURNAL OF THE NATIONAL CANCER INSTITUTE 104:941-952(2012).
