TRIM25

  • Official Full Name

    tripartite motif containing 25
  • Overview

    TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family, and functions as a ubiquitin ligase. Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demo
  • Synonyms

    TRIM25;tripartite motif containing 25;tripartite motif containing 25 , zinc finger protein 147 (estrogen responsive finger protein) , ZNF147;E3 ubiquitin/ISG15 ligase TRIM25;EFP;RNF147;RING finger protein 147;zinc finger protein-147;tripartite mo

Recombinant Proteins

  • Zebrafish
  • Mouse
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • Avi&Fc&His
  • Flag
  • DDK&Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
TRIM25-10521Z Recombinant Zebrafish TRIM25 Mammalian Cells Zebrafish His
TRIM25-17350M Recombinant Mouse TRIM25 Protein Mammalian Cells Mouse His
TRIM25-788HCL Recombinant Human TRIM25 293 Cell Lysate HEK293 Human Non
TRIM25-2253H Recombinant Human TRIM25 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
TRIM25-2253H-B Recombinant Human TRIM25 Protein Pre-coupled Magnetic Beads HEK293 Human
TRIM25-483HFL Recombinant Full Length Human TRIM25 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
TRIM25-5098H Recombinant Human TRIM25 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Trim25-6647M Recombinant Mouse Trim25 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
TRIM25-9597M Recombinant Mouse TRIM25 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
TRIM25-9597M-B Recombinant Mouse TRIM25 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    TRIM25 involved in several pathways and played different roles in them. We selected most pathways TRIM25 participated on our site, such as NF-kappa B signaling pathway,RIG-I-like receptor signaling pathway,Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Influenza A NFKBIA,HNRNPUL1,IFNA16,BLB1,OAS3,PRSS1,Ifna15,NLRP3,LOC100033925,STAT2
    NF-kappa B signaling pathway Ccl21c,TNFSF11,CD40LG,TNFSF14,TRADD,RELA,IRAK4,PLCG2,NFKB1,NFKBIA
    RIG-I-like receptor signaling pathway AZI2,ISG15,IFNA3,DHX58,RIPK1L,IL12B,IFNB,IFNA8,MAP3K7,CASP8

    Protein Function

    TRIM25 has several biochemical functions, for example, acid-amino acid ligase activity,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM25 itself. We selected most functions TRIM25 had, and list some proteins which have the same functions with TRIM25. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin protein ligase activity involved in ERAD pathway RNF185,STUB1,SYVN1,RNF5,TMEM129,PARK2,AMFR
    zinc ion binding RNF222,EWSR1A,TRIM3,NEURL1AB,CBLL1,ZCCHC7,SIVA1,RNF13,ZSWIM2,ISL2B
    protein binding FAM110C,MPP2,NOL12,PPARG,STBD1,ITPR1,MSN,FCN2,PPM1B,PLK1
    poly(A) RNA binding LSM2,NGDN,SNRPD2,CCDC137,RPF2,LTA4H,IFIT5,CSTF1,ABCF1,PCSK9
    acid-amino acid ligase activity RNF41,RAG1,UBA3
    transcription factor activity, sequence-specific DNA binding FOXA1,PCGF2,RFX8,FLI1B,HOXC6,NKX3-1,PPARDB,DMBX1,BACH1A,EOMESB

    Interacting Protein

    TRIM25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM25 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM25.

    DDX58;NS;f1ba49_9viru;NS1;NS1;NS1;NS1;XRCC3;IGF1R;APC

    Resources

    References

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