TRAPPC3
-
Official Full Name
trafficking protein particle complex 3 -
Overview
This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the;cis-Golgi membrane. The encoded protein participates in the regulation of transport from the endoplasmic reticulum to;the Golgi apparatus. Alternative splicing results in multiple transcript variants. -
Synonyms
TRAPPC3;trafficking protein particle complex 3;trafficking protein particle complex subunit 3;BET3;1110058K12Rik;AI835942;AU019197;BET3 homolog;MGC105948;OTTHUMP00000009025;OTTMUSP00000009752;RP23-118D1.2;TRAPPC 3
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- GST
- His&Fc&Avi
- Myc&DDK
Involved Pathway
TRAPPC3 involved in several pathways and played different roles in them. We selected most pathways TRAPPC3 participated on our site, such as Asparagine N-linked glycosylation,COPII (Coat Protein 2) Mediated Vesicle Transport,ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRAPPC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ER to Golgi Anterograde Transport | MCFD2,MIA3,LMAN2L,BET1,SEC16B,TRAPPC6B,TFG,SCFD1,NSFB,PPP6R3 |
| COPII (Coat Protein 2) Mediated Vesicle Transport | SEC22C,SCFD1,TRAPPC6BL,NAPAA,LMAN2,CNIH,CNIH3,TFG,LMAN2L,NAPAB |
| Transport to the Golgi and subsequent modification | TRAPPC2,SEC22C,MGAT4A,PPP6R1,TRAPPC10,NAPB,PPP6R3,MIA3,TRAPPC1,CNIH |
| Post-translational protein modification | PPP6R3,SMC6,TFG,TMED10,SEC22C,PIGK,NSMCE1,GALNT13,PPP6C,EIF5A |
| Metabolism of proteins | DNAJC24,CTSH,F9B,ADAMTS20,GAS6,SUMF2,NEU4,SCMH1,UBA2,A4GNT |
| Vesicle-mediated transport | HIP1R,SEC23IP,COPZ1,CNO,TRAPPC9,BLOC1S4,PPP6C,TRAPPC2,SCFD1,SNAPIN |
| Asparagine N-linked glycosylation | CTSC,TMED10,PREB,ST6GAL2B,SCFD1,LMAN2,SERPINA1L,MAN1A2,TRAPPC6BL,ST6GALNAC1.2 |
| Membrane Trafficking | DTNBP1,YIPF6,CTAGE5,SEC22C,MYO6,BLOC1S1,TRAPPC2L,CPD,PICALMB,EXOC8 |
Protein Function
TRAPPC3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRAPPC3 itself. We selected most functions TRAPPC3 had, and list some proteins which have the same functions with TRAPPC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | EGF,RHOXF2,SNX32,CD59,ANXA11,CDK17,REEP5,RAB33A,TCOF1,RABGGTB |
Interacting Protein
TRAPPC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRAPPC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRAPPC3.
TRAPPC2L;TRAPPC6A;TRAPPC6A;PLEKHF2;TRAPPC6B
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References
- Giam, M; Okamoto, T; et al. Bcl-2 family member Bcl-G is not a proapoptotic protein. CELL DEATH & DISEASE 3:-(2012).
- Neves, V; Gerondopoulos, A; et al. Cellular localization, accumulation and trafficking of double-walled carbon nanotubes in human prostate cancer cells. NANO RESEARCH 5:223-234(2012).
